NPY样免疫反应在蝾螈发育过程中神经系统的定位研究  

STUDIES ON THE LOCALIZATION OF NPYLIKE IMMUNO-REACTIVITY IN THE NERVOUS SYSTEM DURING DEVELOPMENT OF CYNOPS ORIENTALIS

作　　者：张小云[1] 罗振国[1] 曾弥白[2] 

机构地区：[1]深圳大学生物工程系,深圳518060 [2]中国科学院上海细胞生物学研究所,上海200031

出　　处：《实验生物学报》2000年第1期41-51,共11页Acta Biologiae Experimentalis Sinica

基　　金：国家自然科学基金

摘　　要：用免疫组化方法研究在蝾螈胚胎发育中神经肽Y(NPY)在神经系统中的定位。结果表明NPY最早分布在周边神经系统(尾芽晚期),之后才在中枢神经系统出现(幼虫期),而且是随着胶质细胞的出现而出现的。我们认为NPY是随着神经嵴细胞的迁移而进入周边神经系统,再分布到中枢神经系统的。By immuno-cytochemical method the localization of neuropeptide Y (NPY) in the nervous system during embryonic development of Cynops orientalis was studied. The results revealed that NPY was first localized in the peripheral nervous system (late tail-bud stage), and later appeared in the central nervous system (larval stage ) where it appeared with the appearance of glial cells. Very probably with the migration of neural crest cells NPY appeared first in the peripheral nervous system and then distributed to the central nervous system.

关 键 词：神经肽Y 胚胎发育 神经系统 定位 蝾螈 免疫组化 

分 类 号：Q42[生物学—神经生物学]