小细胞肺癌手术治疗与化疗疗效的临床研究  

Clinical effect of operation and chemotherapy on patients with SCLC

作　　者：魏春勇[1] 汪礼旭[1] 李志华[1] 陈亮[1] 

机构地区：[1]深圳市龙岗中心医院,广东深圳518116

出　　处：《中国医药科学》2013年第12期189-190,共2页China Medicine And Pharmacy

摘　　要：目的探讨小细胞肺癌(SCLC)手术联合化疗治疗与单纯化疗的疗效的对比研究。方法回顾性分析从2002年1月～2007年1月我院收治小细胞肺癌患者52例,均经病理组织学证实,其中25例采用手术治疗联用化疗治疗方法,作为联合组,余27例单纯采用化疗治疗方法,作为对照组。结果联合组1年、2年、5年生存率分别为80.0%、44.0%、24.0%;对照组1年、2年、5年生存率分别为48.1%、33.3%、11.1%,两组比较差异有统计学意义(P<0.05)。结论与单纯化疗相比,手术治疗联用化疗治疗能明显延长小细胞肺癌患者的生存时间,具有较好的远期疗效。Objective To compare the therapeutic effects of operation combined with chemotherapy and chemotherapy alone in patients with SCLC. Methods Retrospective analysis was performed on 52 patients with SCLC in our hospital from Jan.2002 to Jan 2007.Among 52 cases,25 cases were treated with operation and chemotherapy as joint group,and 27 cases were treated with only chemotherapy as control group. Results The survival rates in 1 year,2 years and 5 years（80.0%,44.0%,24.0%）were much higher than those in control group（48.1%,33.3%,l 1.1%）,there were significant differenees（P 〈 0.05）. Conclusion The operation combined with chemotherapy in patients with SCLC can obviously prolong the survival time with a better long-term clinical effect.

关 键 词：小细胞肺癌 手术治疗 化疗 

分 类 号：R655.3[医药卫生—外科学]