羊栖菜多糖对高血脂模型大鼠血脂的影响  

Effect of SFPS on hyperlipemia model rats

作　　者：李八方[1] 毛文君[1] 曹立民[1] 

机构地区：[1]青岛海洋大学,山东青岛266003

出　　处：《中国水产科学》2000年第2期56-58,共3页Journal of Fishery Sciences of China

摘　　要：以实验性高血脂模型大鼠为实验对象 ,设置 3个羊栖菜多糖 (SFPS)剂量组 (0 .3、0 .6、1.2 g/kg·d)和阳性、空白对照组 ,观察其调血脂效果。结果表明 ,羊栖菜多糖各剂量组均具有显著抑制高血脂模型大鼠血中总胆固醇 (TC)、甘油三酯 (TG)和低密度脂蛋白胆固醇 (LDL -C)的增长 ,降低其含量 ,升高高密度脂蛋白胆固醇 (HDL -C)含量的作用。 3个剂量组均好于调血脂药物肌醇烟酸酯阳性对照组 ;与空白对照组相比 ,羊栖菜多糖组和阳性药对照组均具有极显著性差异 (P <0 .0 1)。Using hyperlipmia model rats as the experimental animal to observe the effect of Sargassum fusiforme polysaccharide (SFPS) on lipemia, a positive control group (positive drug 100 mg/kg), control group and 3 doses of SFPS groups(0.3, 0.6, 1.2 g/kg·d) were set up. The results show that SFPS at each dose of the 3 groups can inhabit the total cholesterol, triglyceride and low-density lipoprotein cholesterol, even reduce their contents, and can increase the content of high-density lipoprotein cholesterol. All the results in the 3 doses of groups are better than those in the positive control. The SFPS groups and positive control groups present extremely different from the control in the result of regulating lipemia(P<0.01).

关 键 词：羊栖菜多糖 高血脂 调血脂作用 

分 类 号：Q949.288.5[生物学—植物学] R282.710.5[医药卫生—中药学]