金刚藤辅助治疗异位妊娠包块的临床研究  

CLINICAL ANALYZE OF ECTOPIC GESTATION AUXILIARY TREATED BY JINGANGTENG

作　　者：李国慧[1] 宋静慧[1] 陈秀娟[1] 

机构地区：[1]内蒙古医科大学附属医院妇产科,内蒙古呼和浩特010059

出　　处：《内蒙古医科大学学报》2013年第3期179-182,187,共5页Journal of Inner Mongolia Medical University

基　　金：内蒙古教育厅科研项目(NJ10145)

摘　　要：目的:对比中药金刚藤+甲氨蝶呤+米非司酮与甲氨蝶呤+米非司酮保守治疗异位妊娠包块的疗效。方法:选取内蒙古医科大学附属医院妇产科2007-1～2011-1住院行保守治疗的异位妊娠病人90例随机分为实验组45例和对照组45例。实验组给予金刚藤+米非司酮+甲氨蝶呤治疗,对照组给予米非司酮+甲氨蝶呤治疗,比较两组的疗效。统计分析采用SPSS 13.0软件。结果:治疗后实验组血清β-HCG恢复至正常时间、包块吸收时间及输卵管复通率分别为16.13±8.13 d、30.46±7.56 d和80%,而对照组分别为22.05±7.15 d、39.99±18.26 d和75%,两组差异均有统计学意义,而两组在有效率[95.56%(43/45)vs.94%(47/50)]和药物副反应发生率方面,差异无统计学意义。结论:金刚藤辅助治疗异位妊娠在缩短血清β-HCG恢复至正常时间和包块吸收时间,以及改善输卵管功能方面均有明显作用。Objective：To compare the clinical efficacy of conservative treatment of Jingangteng, Methotrexate and Mifepristone to Mifepristone and Methotrexate for masses of ectopic pregnancy. Methods：90 patients with conservative treatment of ectopic pregnancy were randomly divided into two groups,which from January 2007 to January 2011 in the Affiliated Hospital of Inner Mongolia Medical University. 45 cases of these patients with Jingangteng, Methotrexate and Mifepristone therapy as experimental group, other 45 cases treated with Mifepristone and Methotrexate for control group. SPSS 13.0 for Statistical analysis. Result： After treatment the time of blood HCG-13dropped to normal range, masses absorption and fallopian tube repatency is 16.13 ± 8.13 d, 30.46 ±7.56 d and 80% in experimental group, while it is 22.05 ±7.15 d,39.99±18.26 d and 75% in control group, the difference has statistical significance,but between two groups the differences of effective rate[95.56%（43/45）vs94%47/501 and side effects has no statistical significance. Conclusion：The combination of Jingangteng is much more effective in shorten time of blood HCG-βback to normal, masses absorption and fallopian tube repatency.

关 键 词：异位妊娠 甲氨蝶呤 米非司酮 金刚藤 

分 类 号：R984[医药卫生—药品]