云南农村自然人群冠状动脉钙化情况的调查研究  

Research on Coronary Artery Calcification of the Village Population in Yunnan Province

作　　者：刘爱波[1] 吴新华[1] 欧阳天昭[1] 曹慧丽[2] Robert Detrano 陈章荣[1] 匡时权[1] 杨瑛[1] 董瑜[1] 李利华[1] 

机构地区：[1]大理学院附属医院,云南省大理市671000 [2]北京协和医科大学中国医学科学院阜外心血管病医院,北京市100037 [3]University of California Irvine

出　　处：《中国动脉硬化杂志》2013年第6期554-556,共3页Chinese Journal of Arteriosclerosis

基　　金：国家自然科学基金(30960137)

摘　　要：目的观察云南农村自然人群冠状动脉钙化及冠状动脉钙化积分情况。方法对云南农村自然人群进行单纯随机抽样,采用16排螺旋CT对174例研究对象进行冠状动脉扫描,计算冠状动脉钙化,并应用Agatston积分法计算钙化积分,观察冠状动脉钙化及钙化积分的分布特征,按性别、年龄、种族进行分组,比较组间钙化率及钙化积分的差别。结果 174例入选研究对象中39例发现钙化(阳性率22.4%)及钙化积分≥1。51～60岁组、61～71岁组钙化阳性率分别为15.5%、34.4%,钙化积分分别为11.2±52.4、38.0±82.0。钙化阳性率及钙化积分在不同年龄组间有显著性差异(P<0.05),而在性别和种族之间无显著性差异。冠状动脉钙化阳性率为前降支>回旋支=右冠状动脉>左主干。结论云南农村51～71岁自然人群中冠状动脉钙化及钙化积分存在年龄间的差异。钙化发生率最高在前降支,其次为回旋支和右冠状动脉。Aim To observe the characteristics of coronary artery calcium （CAC） and coronary artery calcium score （CACS） in the village population in Yunnan province. Methods Coronary calcium scan with 16-MDCT was performed in 174 cases sampled randomly from the village population in Yunnan province. Coronary artery calcium score was calculated. The characteristics and difference of CAC and CACS were compared between groups of gender, age and race. Results The positive rate of CAC in 174 samples was 22. 4% and 39 samples with CACS≥1, the positive rate of CAC in 51 -60 years group and 61 - 71 years group was 15. 5% and 34. 4% respectively and the CACS was 11.2 ± 52. 4 and 38. 0 ± 82. 0. The difference of CAC and CACS in these groups had remarkable statistical significance （P 〈0. 05）, however, these index between the gender and race had no statistical significance, the positive rate of CAC in coronary artery was LAD 〉 LCX = RCA 〉 LM. Conclusions CAC and CACS had age differences in age group orS1 -71 years of the village population in Yunnan. The highest incidence of CAC was in the left anterior descending artery, followed by left circumflex artery and right coronary artery.

关 键 词：冠心病 冠状动脉钙化 冠状动脉钙化积分 多排螺旋CT 

分 类 号：R18[医药卫生—流行病学]