苯乙醇苷类成分构效关系研究进展  

Progress in Structure-activity Relationship of Phenylethanoid Glycosides

作　　者：吴爱芝[1] 林朝展[1] 祝晨蔯[1] 

机构地区：[1]广州中医药大学中药学院,广州510006

出　　处：《天然产物研究与开发》2013年第6期862-865,共4页Natural Product Research and Development

基　　金：国家自然科学基金项目(81001613)

摘　　要：苯乙醇苷类成分在药用植物中广泛存在,生物活性明显且低毒安全,具有潜在的药用开发价值。本文首次以构效关系为主线,综述了近二十年来该类成分在抗氧化和自由基清除、抗肿瘤、神经元保护、肝脏保护、止痛、抗病毒、抗菌等方面的研究进展。该综述为今后进一步从结构角度较全面地深入探讨苯乙醇苷类成分的生物活性提供了理论依据。Phenylethanoid glycosides （PhGs） are widely distributed in medicinal kingdom of plants. These compounds possess broad biological activities,lower toxicity and good safety, which provide great potentials in pharmaceutical applications. It will be the first occasion to review the progress of antioxidafion,free radical scavenging, antitumor, neum-proteetive, hepatopmteetive,analgesic effects, antiviral and antibacterial activities of PhGs in recent twenty years based on structure-activity relationships as clues. This review will be helpful for comprehensive biological activity researches of PhGs from the point of structure.

关 键 词：苯乙醇苷 生物活性 构效关系 综述 

分 类 号：R284[医药卫生—中药学]