骨质疏松症中医证候疗效评价方法研究  被引量:15

Evaluation Method of TCM Pattern Efficacy for Osteoporosis

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作  者:李东涛[1] 李富玉[1] 王剑[1] 刘继红[1] 程咏梅[1] 燕南[1] 史风雷 姜洪洋 胡爱华[4] 张美增[5] 李洁 魏陵博 姜荣钦 

机构地区:[1]济南军区青岛第一疗养院 [2]青岛市骨伤医院 [3]海阳市中心医院 [4]青岛市社会福利院 [5]青岛大学附属医院 [6]青岛市海慈医疗集团 [7]青岛市中西医结合医院

出  处:《中医杂志》2013年第13期1110-1114,共5页Journal of Traditional Chinese Medicine

基  金:国家中医药管理局资助项目(06-07LP52);青岛市科技局资助项目(07-1-21-nsh)

摘  要:目的探讨以证候为内容的骨质疏松症中医疗效评价方法,并验证其可靠性。方法以100mm刻度法及综合评价层次分析法为数学工具,以综合集成研讨厅为研讨方式,共取36个中医症状量化分值为底层指标,定性证候的各个症状或症状组合为第二层次指标,以精亏、气虚、阴虚、阳虚、血瘀证5个定性证候为第三层次指标,以证候总评价为顶层指标;计算权重,建立优选矩阵,确立各层次指标计算公式,初步构建以证候为内容的骨质疏松症综合疗效评价体系;并通过证候总评分与骨密度、骨质疏松症生存质量的相关性分析,对模型的可靠性进行临床验证。结果分别按100mm刻度法、三级、二级、一级赋分法量化了骨质疏松症36个常见中医症状;确立了精亏证、气虚证、阴虚证、阳虚证、血瘀证各证候及中医证候总评分量化计算公式。临床验证结果显示,骨质疏松症患者中医证候总评分与骨密度、生存质量均有线性关系,相关系数分别为0.842、0.826。结论构建的骨质疏松症中医证候疗效评价方法可反映骨质疏松症患者病情轻重程度,临床验证可靠。Objective To research the evaluation method of TCM pattern efficacy for osteoporosis and verify its reliability. Methods The analytic hierarchy process (AHP) and 100mm surveyor's rod method was applied as mathematical tool. The hall for workshop of metasynthetic engineering (HWME) was applied as discussion method. Thirty-six TCM symptoms were selected as the underlying index, qualitative pattern index (symptoms or symptom combinations) was selected as the secondlevel indicators, 5 qualitative patterns such as essence deficiency, qi deficiency, yin deficiency, yang deficiency and blood stasis were selected as the third-level indicators and the total assessment of TCM pattern was selected as the top-level indicator. The weight was calculated. The preferred matrix and index calculation formula of all levels was established. The comprehensive evaluation system of TCM pattern efficacy for osteoporosis was initially constructed. The reliability was verified according to the correlation of TCM pattern overall score, bone mineral density (BMD) and quality of life (QOL). Results Thirty-six common TCM patterns of osteoporosis were quantified. The calculation formula of essence deficiency pattern, qi deficiency pattern, yin deficiency pattern, yang deficiency pattern, blood stasis pattern and TCM pattern overall score was established. There was a linear correlation between TCM pattern overall score, BMD and QOL and the coefficient was 0. 842 and 0. 826 respectively. Conclusion The evaluation method of TCM pattern efficacy for osteoporosis is reliable and can reflect the disease condition.

关 键 词:骨质疏松症 证候 疗效评价 层次分析法 综合集成研讨厅 

分 类 号:R259[医药卫生—中西医结合]

 

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