剖宫产患者围术期预防用抗菌药物的回顾性分析  

Retrospective Analysis of Perioperative Prophylactic Application of Antibiotics in Patients Underwent Cesarean Section

作　　者：熊伟[1] 李晓霞[1] 张启祥[1] 

机构地区：[1]建德市第一人民医院,浙江建德311600

出　　处：《中国药房》2013年第26期2405-2407,共3页China Pharmacy

基　　金：浙江省医学会临床科研基金项目(No.2011ZYC-A50)

摘　　要：目的:探讨实施干预措施对剖宫产患者围术期预防用抗菌药物的效果。方法:选择我院2011年1-9月归档的300份剖宫产患者病历作为对照组(干预前),2011年10月-2012年6月300份剖宫产患者病历作为干预组(干预后),对两组患者围术期预防用抗菌药物情况进行回顾性对照分析。结果:两组剖宫产患者均100%使用抗菌药物,均为钳夹脐带后静脉给药;干预组抗菌药物预防使用品种选择更加合理,不合理联合用药现象显著减少,用法用量不合格现象明显减少;用药疗程对照组为(4.53±1.35)d,干预组为(2.29±0.55)d,二者比较差异有统计学意义(P<0.05);术后感染发生率,二者比较差异无统计学意义(P>0.05)。结论:我院采取的干预措施具有明显的针对性和实效性,有利于减轻患者的经济负担,提高医院的合理用药水平。OBJECTIVE： To investigate the effects of interventions on perioperative prophylactic application of antibiotics in pa-tients underwent cesarean section. METHODS： 300 cases of cesarean section were selected from our hospital during Jan.-Sept. in 2011 as control group （before intervention）, and 300 cases were selected from Oct. 2011 to Jun. 2012 as intervention group （after intervention）. Perioperative prophylactic application of antibiotics in 2 groups was studied retrospectively. RESULTS： Antibiotics were used in all cases and given after the umbilical cord was clamped. In intervention group, species selection of prophylactic appli- cation of antibiotics was more reasonable and the case number of irrational antibiotics use was decreased significantly; the case number of irrational usage and dosage was decreased significantly. The course of treatment was （4.53 ± 1.35） d in control group and （2.29 ± 0.55）d in intervention group; there was statistical significance （P〈0.05）. There was no statistical significance in the inci- dence of postoperative infection （P〉0.05）. CONCLUSIONS： The intervention measures of our hospital have much more perti-nence and actual effect, which reduce the economic burden of patients and improve the rational use of drugs in hospital.

关 键 词：剖宫产 围术期 抗菌药物 回顾性分析 

分 类 号：R969.3[医药卫生—药理学] R287.978.1[医药卫生—药学]