我院193份新的、严重的药品不良反应报告分析  

Analysis of 193 Cases of New and Severe Adverse Drug Reactions in Our Hospitals

作　　者：石卫峰[1] 高君伟[1] 文冰亭[1] 刘皋林[1] 

机构地区：[1]上海交通大学附属第一人民医院药剂科,上海200080

出　　处：《中国药房》2013年第26期2459-2461,共3页China Pharmacy

摘　　要：目的:了解我院新的、严重的药品不良反应(ADR)发生的特点,为临床安全用药提供参考。方法:对2009-2012年我院上报的新的、严重的ADR进行统计和分析。结果:新的、严重的ADR共193例,其中严重的ADR报告20例,新的ADR报告173例;怀疑药品中抗微生物药和中成药所占比例最大;口服给药和静脉给药是最主要的给药途径;临床表现累及最多的是神经系统损害和胃肠系统损害,其次为全身性损害和皮肤及其附件损害。结论:临床工作者应重视ADR监测,并强化用药指导,以保证患者的用药安全。OBJECTIVE： To investigate the characteristics of new and severe adverse drug reactions （ADR） cases so as to pro-vide reference for safe use of drugs in clinic. METHODS： New and severe ADR cases reported during 2009-2012 were analyzed statistically. RESULTS： 20 of the 193 were severe ADR cases and 173 were new. Anti-microbial drugs and proprietary Chinese med- icines accounted for the largest proportion in suspected drugs. Oral and intravenous administrations are the most important routes of administration. The most common clinical manifestations are nervous system damage and gastrointestinal system damage, followed by systemic damage and skin and its appendages damage. CONCLUSIONS： Clinicians should pay attention to the ADR monitoring and strengthen medication guidance to ensure the safety of the patient＇s medication.

关 键 词：药品不良反应 新的 严重的 报告 

分 类 号：R969.3[医药卫生—药理学]