岗梅根中一个新的三萜皂苷(英文)  

A new triterpenoid glycoside from the roots of Ilex asprella

作　　者：赵钟祥[1] 林朝展[2] 祝晨蔯[2] 何文江[1] 

机构地区：[1]广州中医药大学中药学院,广州510006 [2]广州中医药大学临床药理研究所,广州510405

出　　处：《中国天然药物》2013年第4期415-418,共4页

基　　金：supported by the National Natural Science Foundation of China(Nos.81270054,30901954);Specialized Research Fund for the Doctoral Program of Higher Education(No.20094425110008);the project of Zhu Jiang New Star of Science and Technology in Guangzhou city(No.2011J2200047)~~

摘　　要：目的:研究岗梅根的化学成分。方法:采用硅胶、反相硅胶、Sephadex LH-20等柱色谱法对岗梅根的化学成分进行分离纯化,应用谱学技术和化学方法鉴定化合物的结构。结果:从岗梅根中分离并鉴定了4个三萜苷类化合物:(3β)-19-hydroxy-28-oxours-12-en-3-yl β-D-glucopyranosiduronic acid n-butyl ester(1),ilexasoside A(2),Monepaloside F(3)和ilexoside A(4)。结论:化合物1为新化合物,化合物3和4为首次从该植物中分离得到。AIM： To study the chemical constituents of the roots ofllex asprella Champ. ex Benth. METHODS： Compounds were isolated by silica gel, ODS, and Sephadex LH-20 column chromatography, and their structures were elucidated on the basis of phys- icochemical properties and spectroscopic analysis. RESULTS： Four triterpenoid glycosides were isolated and identified as （3β）-19-hydroxy-28-oxours-12-en-3-yl fl-D-glucopyranosiduronic acid n-butyl ester （1）, ilexasoside A （2）, monepaloside F （3）, and ilexoside A （4）. CONCLUSION： Compound 1 is a new triterpenoid glycoside, and compounds 3 and 4 were isolated from this plant for the first time.

关 键 词：岗梅 三萜皂苷 五环三萜 

分 类 号：R284.1[医药卫生—中药学]