过渡金属催化的C—H键活化/C—C键偶联反应  

Research progress of C—H activation/C—C coupling reactions catalyzed by transition metals

作　　者：杨晓燕[1,2] 赖文勇[1] 黄维[1] 

机构地区：[1]南京邮电大学信息材料与纳米技术研究院,有机电子与信息显示国家重点实验室培育基地,南京210023 [2]内蒙古大学化学化工学院,呼和浩特010021

出　　处：《中国科技论文》2013年第6期492-500,共9页China Sciencepaper

基　　金：高等学校博士学科点专项科研基金资助项目(20093223120004);国家重点基础研究发展计划(973计划)资助项目(2009CB930601);国家自然科学基金资助项目(20904024;51173081;61136003;61106036);教育部创新团队计划资助项目(IRT1148);江苏省自然科学基金资助项目(BK2011760);南京邮电大学攀登计划资助项目(NY210016;NY211124);江苏省"青蓝工程"资助项目

摘　　要：过渡金属催化C—H键活化/C—C键偶联反应是当前有机合成的热点之一,已经成为有机合成中构建C—C键的强大工具,能够高选择性、高效合成具有特殊精细骨架结构的化合物。目前最常用的催化剂是钯(Pd)、钌(Ru)和铑(Rh)络合物,此外,廉价、易得、具有独特催化性能的Fe、Co等络合物也引起了越来越多的关注。笔者对过渡金属催化的C—H键活化/C—C键偶联反应的最新研究进展进行了综述。C-H activation/C-C coupling reactions catalyzed by transition metals, which are one of the most popular approaches in modern organic synthesis, have emerged as a powerful tool for making C-C bonds, allowing access to unconventional and e laborated skeletal structures with high selectivity and efficiency. In the field of C-C bond formation via C-H activation, several catalytic reactions have been developed recently, mainly involving complexes of low-valent transition metals such as palladium （Pd）, ruthenium （Ru） and rhodium （Rh）. Furthermore, the first-row transition metal catalysts, such as iron （Fe） and cobalt （Co） complexes, have drawn much attention due to their ready availability, low cost, relatively low toxicity and unique catalytic abilities. Recent advances achieved in this field have been summarized in this paper.

关 键 词：C-H键活化 C-C键偶联反应 过渡金属 

分 类 号：O643.32[理学—物理化学]