清热解毒通腑活血中药联合西药治疗SAP患者的临床疗效观察  

Clinical observation of the effects of the treatment of “Qingrejiedu and Tongfuhuoxue” combined with conventional western medicine for the patients with SAP

作　　者：喻玉[1] 陈辉[1] 向未[1] 肖国辉[1] 李志[1] 

机构地区：[1]泸州医学院附属中医医院消化内科,四川泸州646000

出　　处：《泸州医学院学报》2013年第3期241-243,共3页Journal of Luzhou Medical College

基　　金：四川省中医药管理局基金资助(2010-55);泸州市科技局基金资助(2010-41)

摘　　要：目的:探讨应用清热解毒通腑活血中药联合西药治疗重症急性胰腺炎(SAP)的临床疗效。方法:将重症急性胰腺炎患者99例随机分为实验组(51例)和对照组(48例),均接受西医常规治疗。在此基础上实验组给予清热解毒通腑活血中药的综合治疗,即胰瘅1号、胰瘅2号管胃和灌肠,胰瘅贴外敷胰区腹壁,对照组仅予以西药常规治疗。观察治疗后第1、2、3、7、14d的症状、体征、CT,并进行量化评分。结果:两组治疗后,实验组于第3d、第7d症候与体征评分明显低于对照组,差异有统计学意义(P<0.05);实验组于第3d CT评分及APACHE-II评分下降更明显,差异有统计学意义(P<0.05)。结论:早期联合应用清热解毒通腑活血中药治疗SAP可提高临床疗效,值得推广。Objective： To discuss the clinical efficacy of application of ＂Qingrejiedu and Tongfuhuoxue drugs in early course of conventional western medicine treatment of severe acute pancreatitis（SAP）.Methods： 99 patients with severe acute pancreatitis were randomly divided into experimental group（51 cases） and control group（48 cases）,both underwent routine western medicine treatment.Experimental group was given Qingrejiedu and Tongfuhuoxue＂ drugs,that was YIDAN No.1 and No.2 by enema,and YIDAN paste for external application,2,3,7 and 14 days after the beginning of treatment the symptoms,signs and CT were quantified and scored.Results： After treatment,in the experimental group at the third day,and the seventh day,the clinical symptoms and signs score were significantly lower than that in control group,the difference was statistically significant（P 0.05）;at the third day,CT score decreased more significantly,the difference was statistically significant（P0.05） Conclusion： The early combination of ＂Qingrejiedu and Tongfuhuoxue＂in the treatment of severe acute pancreatitis can improve the clinical efficacy,which is worthy of promotion.

关 键 词：清热解毒通腑活血 胰瘅1号、胰瘅2号 胰瘅贴 重症急性胰腺炎 

分 类 号：R285.5[医药卫生—中药学] R256.49[医药卫生—中医学]