随机尿 晨尿24h尿视黄醇结合蛋白/尿肌酐与24h尿蛋白的相关性研究  

Correlation analysis of urinary retinal binding protein/urinary creatinine ratio in random urine, morning voiding urine and 24 h urine with 24 h urinary quantitative protein

作　　者：袁育林[1] 覃桂芳[1] 杜武杰[1] 阳文辉[1] 赵红英[1] 熊礼佳[2] 

机构地区：[1]广西壮族自治区人民医院检验科,南宁530021 [2]广西壮族自治区人民医院泌尿内科,南宁530021

出　　处：《中国临床新医学》2013年第6期512-514,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西卫生厅科研课题(编号:Z2012258)

摘　　要：目的研究用肌酐校正随机尿、晨尿、24h尿视黄醇结合蛋白(URBP)后与24h尿蛋白(UP)定量的相关性。方法收集泌尿内科住院或门诊患者同一天内随机尿、晨尿和24h尿标本,分别测定三种不同类型尿液中的视黄醇结合蛋白(RBP)、肌酐(Cr)以及UP含量,其中晨尿和随机尿的结果分别以肌酐比值表示。结果 24h URBP与24h UP的相关性为0.955(P=0.000);随机尿、晨尿URBP与24h URBP的相关系数分别为0.663、0.707(P=0.000),与24h UP的相关系数分别为0.673、0.738(P=0.000),其结果经尿肌酐校正后与24h UP的相关系数分别为0.792、0.880(P=0.000)。结论晨尿、随机尿URBP/UCr比值与24h尿蛋白有良好的相关性,且标本收集方便易行。Objective To study the correlations between the retinal binding protein to creatinine ratio in ran- dom urine, morning voiding urine and 24 h urine and the 24 h protein. Methods The random urine, morning voiding urine and 24 h urine of patients were collected in the same day, and retinal binding protein, microalbumin, and cre- atinine were detected respectively. The results of random urine and morning voiding urine should be expressed in ratios with creatinine. Results There were good correlations of 24 h urinary retinal binding protein and 24 h urinary pro- tein. The correlation coefficient was 0. 955（P =0. 000）. The correlation coefficients of retinal binding protein in ran- dom urine and morning voiding urine with 24 b retinal binding protein were 0. 663,0. 707 （P = 0. 000） , and with 24 h urinary protein were 0. 673,0. 738（P =0. 000）. The correlation coefficients of retinal binding protein/creatinine in random urine and morning voiding urine with 24 h urine protein were 0. 792,0. 880 （ P = 0. 000）. Conclusion It is suggested that there is a significant correlation between the ratio of retinal binding protein/ereatinine in random urine or morning voiding urine and 24 hour urinary quantitative protein, and both of the sample can be obtained easily.

关 键 词：24 h尿 晨尿 随机尿 尿蛋白 尿视黄醇 尿肌酐 

分 类 号：R446.12[医药卫生—诊断学]