广东地区455例多囊卵巢综合征患者的临床特征研究  

Research of the Clinical Characteristics of 455 Cases of Polycystic Ovary Syndrome in Guangdong Region

作　　者：韩芸[1] 黄健玲[2] 钟秀驰[2] 吴君[3] 

机构地区：[1]滨州医学院,山东烟台264003 [2]广东省中医院,广东广州510120 [3]山东中医药高等专科学校,山东烟台264199

出　　处：《世界中西医结合杂志》2013年第6期612-614,共3页World Journal of Integrated Traditional and Western Medicine

基　　金：广东省中医药局科研课题(2010156)

摘　　要：目的分析广东地区多囊卵巢综合征(PCOS)患者的临床、内分泌特征和超声特征。方法回顾性分析PCOS患者455例,对其临床表现、内分泌变化及超声征象进行统计分析。结果455例PCOS患者中,月经异常占73.2%,不孕占49.0%,肥胖发生率33.4%。高雄激素血症的发生率28.6%。胰岛素抵抗的发生率为47.7%。TG升高占17.4%,TC升高占27.3%,HDL-C降低占18.9%,LDL-C升高占31.2%。395例B超显示双卵巢多囊改变。48例单侧卵巢多囊改变。结论PCOS患者月经异常、IR的发生率与欧美相似,而肥胖的发生率低于欧美国家,PCOS患者存在严重的内分泌及代谢紊乱。Objective To analyze the clinical endocrinal and ultrasonic characteristics of polycystic ovary syndrome（PCOS） in Guangdong region. Methods The retrospective analysis was done on 455 cases of PCOS. The clinical manifestations, endocrinal changes and ultrasonic signs were analyzed statistically. Results Of 455 cases of PCOS, abnormal menstruation accounted for 73.2% and infertility for 49.0% ; the inci- dence of obesity was 33.4% ,28.6% for hyperandrogenemia and 47.7% for insulin resistance（IR） ;the per- centage of TG increasing was 17.4% ,27.3% for TC increasing, 18.9% for HDL - C reducing and 31.2% LDL - C increasing. Three hundred and ninety - five cases indicated bilateral polycystic ovary changes in ul- trasonic image and 48 cases showed unilateral polycystic ovary changes. Conclusion The incidences of ab- normal menstruation and IR in PCOS patients are similar to the statistical result in European and American regions,but the incidence of obesity is lower than that in European countries and the United State. PCOS pa- tients have serious endocrinal and metabolic disturbance.

关 键 词：多囊卵巢综合征 代谢 内分泌 超声 

分 类 号：R711.75[医药卫生—妇产科学]