165例系统性红斑狼疮患者血液系统受累情况分析  

Analysis of hematological system involvement in 165 patients with systemic lupus erythematosus

作　　者：李春先[1] 

机构地区：[1]聊城市人民医院,山东聊城252000

出　　处：《山东医药》2013年第14期40-41,共2页Shandong Medical Journal

基　　金：聊城市科技技术发展计划政策引导类项目(2010ZC008)

摘　　要：目的探讨系统性红斑狼疮(SLE)患者血液系统受累特点,为其诊治提供依据。方法对165例确诊的SLE患者血液系统受累情况进行回顾性分析。结果本组96例有贫血,其中慢性疾病性贫血(ACD)63例,自身免疫性溶血性贫血(AIHA)11例;72例外周血白细胞下降,65例血小板下降。49例行骨髓检查,以增生活跃为主(44例)。结论 SLE血液系统受累发生率高、范围广。对血象异常的育龄女性患者应注意进行SLE的相关筛查。对于诊断为AIHA或特发性血小板减少性紫癜的患者,应警惕同时存在SLE的可能性。Objective To investigate the characteristics of hematological system involvement in systemic lupus erythe- matosus （SLE） and to provide evidence for its diagnosis and treatment. Methods Retrospective analysis was performed in SLE patients with hematological system involvement. Result A total of 96 in 165 SLE patients with hematological system involvement had anemia, 63 of which had characteristics of anemia caused by chronic disease, 11 had autoimmune hemolytic anemia. A total of 72 patients had a white blood cell count 〈 4 ＊ 10^9/L and 65 patients had a platelet count 〈 100 ＊ 10^9/L. .And 49 of the 165 SLE patients underwent bone marrow examination, mainly hyperplasia. Conclusion Systemic lupus erythematosus （SLE） had a high rate of hematological abnormality, widely involved in hematological system. For women of childbearing age with hematological abnormality, possibility of SLE should be screened. Meanwhile, the combination of SLE in patients with AIHA or idiopathic thrombocytopenic purpura should be on the alert.

关 键 词：系统性红斑狼疮 贫血 白细胞减少 血小板减少 

分 类 号：R383[医药卫生—医学寄生虫学]