健康成年人肾脏不同部位的DTI研究  

DTI Study of Different Parts of the Kidney in Healthy Adults

作　　者：冯强[1,2] 马智军[2] 伍建林[3] 张万伟[2] 辛毅[2] 

机构地区：[1]天津医科大学研究生院 [2]潍坊市益都中心医院CT-MR科 [3]大连大学中山医院放射科

出　　处：《中国医学计算机成像杂志》2013年第3期231-234,共4页Chinese Computed Medical Imaging

摘　　要：目的:探讨年龄、性别及肾脏不同部位对DTI测量指标的影响。方法:收集60例正常志愿者行MR DTI成像检查,男女性各占30例,年龄分三组(40岁以下)、(40-60岁)、(60岁以上),每组20例,比较不同性别、年龄段及肾脏部位对ADC值、FA值的影响。结果:肾实质与肾皮质、髓质的ADC值存在相关性(r=0.91和0.92,P<0.01);肾实质与肾皮质、髓质的FA值存在相关性(r=0.90和0.88,P<0.01);不同性别、年龄段之间肾实质ADC、FA值比较均不具有统计意义(P>0.05),但肾实质ADC值随年龄段的增大逐渐减小,FA值随年龄段增大而逐渐增大;肾脏皮、髓质的上、中、下极ADC值、FA值比较均不具有统计学意义(P>0.05),左右侧比较不具有统计学意义(P>0.05)。结论:研究正常人肾脏ADC、FA值的变化特点,为今后肾脏疾病的诊断和鉴别诊断提供科学可靠的依据。Purpose： To explore the impact of age, gender, and kidney in different parts on DTI measurement. Methods： Sixty normal volunteers scanned by MR DTI imaging were included in our study. There were 30 cases of men and 30 cases of women. According to their ages, they were divided into three groups with 20 patients each： 40 years, 40-60 years, and over 60 years old. The effects of gender, ages and kidneys parts on ADC value and FA value were analyzed. Results： Correlation was existed among ADC values of renal parenchyma and renal cortex, medulla （r = 0.91 and 0.92, P 〈0.01）; the same correlation was existed among FA values of them （r = 0.90 and 0.88, P 〈0.01）. No statistical difference of renal ADC and FA values was found between different gender and age groups （P〉 0.05）, renal ADC values decreased with the increase of age, the tendency of FA values was the converse. No statistical significant difference of ADC value and FA values was found among upper, middle and lower part of renal cortex and medulla （P〉0.05）. No statistical significant difference of ADC and FA values was found between the left and right kidney （p〉0.05）. Conclusion： It is valuable to study normal volunteers, which can provide reliable scientific basis for the diagnosis and differential diagnosis of kidney disease in the future.

关 键 词：肾脏 弥散张量成像 ADC中 FA值 

分 类 号：R445.2[医药卫生—影像医学与核医学]