安肾丸质量标准研究  

Study on Quality Standard for Anshen Wan

作　　者：谭洪泉[1] 马玉梅 李岩[3] 

机构地区：[1]四平市食品药品检验所,吉林四平136000 [2]深圳市泰康制药有限公司,广东深圳518110 [3]吉林省脑科医院,吉林四平136000

出　　处：《中国现代中药》2013年第6期510-513,共4页Modern Chinese Medicine

摘　　要：目的:为了更好地控制安肾丸质量,建立了新的安肾丸质量标准。方法:采用HPLC测定安肾丸中苦杏仁苷的含量。采用TLC对制剂中的肉苁蓉、补骨脂、白术分别进行定性鉴别。结果:苦杏仁苷在10.25～512.5μg线性关系良好,r=0.9999,平均回收率98.91%,RSD=0.48%。TLC可以鉴别出肉苁蓉、补骨脂、白术的特征斑点。结论:实验方法专属性强、重复性好、准确、简便,可有效地控制安肾丸的质量。Objective：To better control the quality of Anshen Wan,establish a new quality standard.Methods：The contents of amygdalin in Anshen Wan were deterrmined by HPLC.Cistanches Herba, Psoraleae Fructus and Atractylodis Macrocephalae Rhizoma were identified by TLC.Results：The resolutons of the determined peaks of Amygdalin were fine at the lineatity range of 10.25～512.5 μg.The average recoveries were 98.91% with RSD 0.48%,for Amygdalin respectively.The characteristic spots of Cistanches Herba, Psoraleae Fructus and Atractylodis Macrocephalae Rhizoma could be detected by TLC.Conclusion：The method is simple,accurate and good in stability,specificity and repeatability,can be used to control quality of Anshen Wan.

关 键 词：安肾丸 HPLC TLC 苦杏仁苷 

分 类 号：R286.0[医药卫生—中药学]