尿激酶和肝素钠在断指再植术后的应用  

Comparison of curative effect of urokinase and heparin sodium after digital replantation

作　　者：吴晓华[1] 樊涛[1] 严明忠[1] 

机构地区：[1]解放军第188医院骨科,广东潮州521000

出　　处：《局解手术学杂志》2013年第4期384-385,共2页Journal of Regional Anatomy and Operative Surgery

摘　　要：目的对比分析尿激酶和肝素钠应用在断指再植术后的治疗效果。方法将259例断指伤患者随机分成尿激酶组130例(217指)和肝素钠组129例(199指),在基础治疗相同的情况下,分别使用尿激酶、肝素钠对再植术后断指进行治疗,比较2组的血管危象发生率、患指成活率、功能恢复等情况。结果在尿激酶组、肝素钠组中,血管危象发生率分别为26.7%和36.7%(P<0.05),患指成活率分别为88.9%和81.9%(P<0.05),活动功能优良率分别为69.3%和53.8%(P<0.05)。结论在断指再植术后治疗中,尿激酶较肝素钠更能减少血管危象的发生率,提高患指的成活率,促进患指功能恢复。Objective To contrast the curative effect of urokinase and heparin sodium after digital replantation. Methods All of 259 patients were randomly divided into urokinase group with 130 eases（217 fingers） and Hepafin sodium group with 129 cases （ 199 fingers）. Two groups received the same basic therapy,and respectively injected with urokinase and heparin sodium. The incidence rate of vascular cri- sis, survival percent of fingers and the recovery of finger function of two group were compared. Restflts The incidence rate of vascular crisis was 26.7 % and 36.7% （P 〈 0.05 ）, the survival percent of fingers was 88.9% and 81.9% （P 〈 0.05 ）, the excellent and good rate of finger function was 69.3 % and 53.8% （ P 〈 0.05 ）, in 2 groups respectively. Conclusion Urokinase has more advantages than heparin sodium in treatment after digital replantation, with reducing the occurrence of vascular crisis, improving the survival rate of replantation of finger and pro- moting the finger function recovery.

关 键 词：尿激酶 肝素钠 断指再植 

分 类 号：R684.7[医药卫生—骨科学] R687.4[医药卫生—外科学]