花红片中七种中草药抗氧化活性研究  

Study on antioxidant activity of seven Chinese medicinal herbs for Huahong Tablet

作　　者：彭妹[1] 庞丽 张艳华 王立升[1] 薛井中[3] 刘帅兵[3] 

机构地区：[1]广西大学化学化工学院,广西南宁530004 [2]广西花红药业股份有限公司,广西柳州545005 [3]广西中医学院药学院,广西南宁530001

出　　处：《广西大学学报（自然科学版）》2013年第3期554-558,共5页Journal of Guangxi University（Natural Science Edition）

基　　金：广西科技攻关项目(桂科攻11107010-3-5);广西自然科学基金重点项目(2010GXNSFD013040)

摘　　要：为了比较花红片原料七种不同中草药(白背叶根、菥蓂、鸡血藤、桃金娘根、一点红、地桃花、白花蛇舌草)的体外抗氧化活性,通过测定各药材的还原能力及其对二苯基苦基苯肼自由基(DPPH.)和羟基自由基(.OH)的清除能力及抑制油脂的氧化能力,评价七种中草药提取物抗氧化活性,并以阳性对照抗坏血酸(Vc)和花红片比较。结果表明:不同中草药显示出不同的抗氧化活性,在七种中草药中,白背叶根和桃金娘根的抗氧化活性较高,对二苯基苦基苯肼自由基(DPPH.)和羟基自由基(.OH)的清除能力及还原能力较好,但均弱于阳性对照Vc的。抑制油脂的氧化能力以鸡血藤最强,但弱于阳性对照Vc。可见,七种药材中以白背叶根和桃金娘根药材的抗氧化活性最强。To research antioxidant activity of seven Chinese medicinal herbs （ root of Mallotus apelta , Thlaspi arvense Linn, Spatholobi caulis , root of Rhodornyrtus to mentosa, Emilia sonchifolia Linn, Urena lobata L. and Hedyotis diffusa Wild） for Huahong Tablet, the samples were tested for reducing capacity of Fe^3＋ , scavenging effects on the DPPH free radical and the hydroxyl radical, and inhibiting capacity of oil oxidation. The four indexes were used to evaluate the antioxidant zctivities for the herbals in vitro with the ascorbie acid and Huahong Tablet as positive control samples. The results indicated that the different kinds of Chinese herbal medicine had different antioxidant activities. Among seven herbs roots of MaUotus apelta and Rhodomyrtus tomentosa showed the highest antioxidant activity, better reducing capacity, scavenging effects on the DPPH free radical and the hydroxyl radical, but their activities were still inferior to the ascorbic acid. Inhibiting capacity of oil oxidation of these herbs was slightly weaker than that of the ascorbic acid while root of Rhodomyrtus tomentosa is the best among the herbs.

关 键 词：花红片 中草药 抗氧化 自由基 

分 类 号：R282.71[医药卫生—中药学]