健康飞行员中心动脉反射波增强指数的测定及其临床应用  

The measurement of augmentation index of central artery and its clinical application in healthy pilots

作　　者：王新宴[1] 张龙方[2] 许波[1] 黄翠莹[1] 尉驰[1] 王建昌[3] 

机构地区：[1]空军总医院特诊科,北京100142 [2]空军总医院超声诊断科,北京100142 [3]空军总医院,北京100142

出　　处：《空军医学杂志》2013年第1期22-24,共3页Medical Journal of Air Force

基　　金：全军"十二五"后勤科研重大项目(AKJ11J004)

摘　　要：目的初步观察我军健康现役飞行员中心动脉反射增强指数(augmentation index,AIx)的变化及其影响因素,为招飞及现役飞行员心血管疾病的预防、治疗提供参考。方法采用无创主动脉搏波分析仪(Sphygmocor)对在空军总医院住院、体检、改装的58例现役飞行员中心动脉收缩压(cSBP)及AIx进行定量检测,并随机选择住院体检的63例健康男性人群作为对照组,两组间进行年龄、血压配对比较无差异,并经病史询问无心血管疾病史,体格检查无阳性体征。心电图、X线胸片、肝肾功能、生化全套等检查无异常者。结果两组间临床资料及生化检测指标的比较无统计学差异(P>0.05),健康飞行员组AIx值低于对照组(P<0.05),相关性分析结果表明AIx与年龄呈正相关(飞行员组:r=0.367,P<0.05)。多元逐步回归分析示年龄、cSBP、收缩压、舒张压是健康飞行员AIx的主要影响因素。结论健康飞行员AIx值低于正常健康人,但受年龄、cSBP、收缩压、舒张压影响。AIx值可为招飞及飞行员心血管疾病的预防、治疗提供理论参考。Objective We intended to observe the changes of augmentation index（AIx） of central artery and its influence factors in healthy military pilots,to provide reference for pilot recruitment,and to present references for prevention and treatment of cardiovascular diseases in active pilots.Methods Using Sphygmocor,the central artery systolic blood pressure（cSBP） and AIx were quantitatively detected in 58 active pilots who were hospitalized or took physical examination for pilot transition.Forty-nine healthy male subjects who were hospitalized for physical examination were randomly selected as control group.There were no differences between two groups regarding age and blood pressure.They had no history of cardiovascular diseases,and had no positive signs during physical examination,and had no abnormal results regarding ECG,chest x-ray,hepatic function,kidney function and biochemistry panel.Results Between the two groups,there were no statistically significant differences regarding clinical data and biochemistry index（P0.05）.With regard to AIx value,it was lower in healthy pilot group than that in control group（P0.05）.Correlation analysis revealed that AIx was positively correlated with age（pilot group,r=0.367,P0.05）.The multiple stepwise regression analysis showed that age,cSBP,systolic blood pressure and diastolic blood pressure were main influencial factors of AIx in healthy pilots.Conclusions In healthy pilots,the AIx value was lower than that in healthy subjects,but it was influenced by age,cSBP,systolic blood pressure and diastolic blood pressure.The AIx value could provided theory references for pilot recruitment and prevention and treatment of cardiovascular diseases in pilots.

关 键 词：飞行员 反射波增强指数 动脉 僵硬度 

分 类 号：R851.1[医药卫生—航空、航天与航海医学]