慢性阻塞性肺病(COPD)血清钙磷水平的临床意义初步研究  

Serum calcium and phosphorus levels in COPD

作　　者：袁成[1] 程际云[1] 周琳[1] 黄茂[1] 姚欣[1] 

机构地区：[1]南京医科大学第一附属医院呼吸科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2013年第6期824-826,共3页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金资助(81070025);江苏高校优势学科建设工程资助(JX10231801);科技部科技重大专项"重大新药创制"(2011ZX09302-003-02)资助

摘　　要：目的:研究慢性阻塞性肺病(COPD)患者肺功能与机体钙磷代谢的相关性。方法:提取COPD患者、吸烟者及非吸烟对照者的肺功能、血清钙磷、是否合并高血压等相关数据进行回顾性分析。结果:与吸烟组和对照相比,COPD组血清钙磷水平降低(P<0.05和P<0.01)。是否合并高血压对COPD血清钙磷水平无明显差异(P>0.05)。在COPD组中肺功能与机体血清钙磷水无明显相关性(P>0.05)。结论:COPD患者存在钙磷代谢异常,但其血清钙磷水平与肺功能状态未体现明显相关。Objective：To investigate the correlation between lung function and serum calcium and phosphorus levels in COPD patients.Methods：Lung function,serum calcium,phosphorus data were collected from COPD group,smoking group and control group for a retrospective analysis.Results：Compared with the smoking group and control group,the serum calcium and phosphorus levels were decreased in COPD patients（P〈0.05 and P 0.01,respectively）.Hypertension had no effect on serum calcium and phosphorus levels（P〈0.05） in COPD patients.Lung function in COPD group was not significantly related to serum calcium and phosphorus levels（P〈0.05）.Conclusion：There is a metabolic abnormality of calcium and phosphorus in COPD patients,although no relationship was shown between lung function and serum calcium and phosphorus levels.

关 键 词：钙 磷 肺功能 COPD 吸烟 

分 类 号：R563.5[医药卫生—呼吸系统]