386例主动脉夹层患者早期药物治疗控制心率和血压效果分析  

Effect of the early drugs treatment in control of heart rate and blood pressure for 386 cases with aortic dissection

作　　者：陈娟[1] 蔡绍乾[2] 周颜慧[2] 肖志超[2] 郭小梅[2] 

机构地区：[1]湖北省鄂州市优抚医院 [2]华中科技大学同济医学院附属同济医院,武汉430030

出　　处：《内科急危重症杂志》2013年第3期149-150,共2页Journal of Critical Care In Internal Medicine

基　　金：国家自然科学基金资助项目(No:81270353)

摘　　要：目的:探讨内科药物治疗控制心率和血压达标对主动脉夹层(AD)患者近期住院生存率的影响。方法:对386例AD患者的药物治疗情况进行回顾性分析。结果:6h内收缩压降低至120mmHg以下和/或心率维持在50～60次/min患者较心率和血压未达标者近期存活率显著提高,特别是心率和血压双达标者24h生存率和住院期间生存率最高。结论:强化控制心率和血压是内科药物治疗AD的关键,可提高AD患者近期生存率。Objective： To explore the effect of the early drug treatment in control of heart rate and blood pressure on short term survival rate for the patients with aortic dissection （AD）. Methods： Drug treatment of 386 cases with aortic dissection were analyzed retrospectively. Results ： The early survival rate of patients with systolic blood pressure less than 120 mmHg or / and heart rate within 50 to 60 beats per minute attained within 6 hours after admission was higher than those patients with systolic blood pressure more than 120 mmHg or / and heart rate over 60 beats per minute. Conclusions ： Actively controlling blood pressure and heart rate to the target level was the most effective medical treatment to increase the early survival rate for the patients with aortic dissection.

关 键 词：主动脉夹层 药物治疗 生存率 

分 类 号：R543.1[医药卫生—心血管疾病]