急性心肌梗死患者的临床特点与低游离三碘甲腺原氨酸的相关性研究  

Relationship of acute myocardial infarction patients clininc characteristic and free triiodothyronine level

作　　者：黎娜[1] 侯丕华[2] 申京波[1] 李宪伦[1] 叶小钧[1] 张丽芳[1] 崔超英[1] 

机构地区：[1]中日友好医院心内科,北京100029 [2]中日友好医院高干保健一病区,北京100029

出　　处：《中国医药导报》2013年第19期60-62,65,共4页China Medical Herald

基　　金：中央保健科研课题(编号B2009D099)

摘　　要：目的探讨急性心肌梗死（acute myocardial infarction,AMI）患者的临床特点与低游离三碘甲腺原氨酸（freetriiodothyronine,FT3）的关系。方法选择2012年10月～2013年3月中日友好医院收治的AMI并行冠状动脉造影（coronary angiography,CAG）的患者共106例。收集研究对象的临床和CAG资料,对其进行回顾性研究。结果 106例患者中54例（50.9%）FT3减低,52例（49.1%）FT3正常。低FT3组和正常FT3组糖尿病的发生率分别为40.74%、19.23%（P=0.000）;左室射血分数分别为（50.00±11.90）%、（56.67±12.84）%（P=0.045）;血红蛋白分别为（129.27±19.31）、（139.64±17.99）g/L（P=0.041）;与正常FT3组比较,低FT3组心功能差,KillipⅠ级患者比例少,KillipⅣ级患者比例多,梗死相关动脉多为前降支（left anterior descending,LAD）,右冠状动脉病变少,差异有统计学意义（P〈0.05）。结论 AMI患者发生低FT3比例高,低FT3组糖尿病发生率高、心功能差、血红蛋白低、冠脉LAD病变多。Objective To investigate the relationship between acute myocardial infarction （AMI） patients clininc characteristics and free triiodothyronine （FT3） level. Methods This retrospective study invovled 106 patients with AMI who underwent coronary angiography （CAG）. All patients were admitted and treated in China-Japan Friendship Hospital from October 2012 to March 2013. Their clinical features and CAG were evaluated. Results There were 54 （50.9%） patients in the low FT3 level group and 52 （49.1%） patients in the normal FF3 level group. In the low FT3 level group and normal FT3 level group, diabetes mellitus incidences were 40.74% and 19.23% respectively （P = 0.00）, left ventricule ejection fraction （LVEF） was （50.00±11.90）% and （56.67±12.84）% respectively （P = 0.045）, hemoglobin was （129.27±19.31） and （139.64±17.99） g/L respectively （P = 0.041）, all the differences were statistically significant.Compared with patients in the normal FT3 level group, patients in the low FT3 level group had poor heart function, patients with Killip Ⅰ were less, Killip Ⅳ were more, infarct-related artery being left anterior descending （LAD） was more frequent, being right coronary artery（RCA） was less frequent, all the differences were statistically significant （P 〈 0.05）. Conclusion A low FT3 level has a high incidence in patients with AMI. Diabetes mellitus incidence is higher, cardiac function is worse,hemoglobin is lower, IRA being LAD are more frequent in low FF3 level group.

关 键 词：急性心肌梗死 低游离三碘甲腺原氨酸水平 心功能 冠脉造影 

分 类 号：R542.22[医药卫生—心血管疾病]