壳聚糖智能水凝胶及其在药物缓释方面的应用  

The chitosan intelligent hydrogel and the application in drug release

作　　者：张素梅[1] 朱文渊[2] 龚红升[1] 廖列文[1] 

机构地区：[1]仲恺农业工程学院化学化工学院,广东广州510225 [2]广州医学院基础学院,广东广州510182

出　　处：《仲恺农业工程学院学报》2013年第2期67-70,共4页Journal of Zhongkai University of Agriculture and Engineering

基　　金：广东省"十一五"农业科技计划项目"农用保水剂的环境生物降解研究"(2009B020311015)资助

摘　　要：壳聚糖具有良好的生物相容性和生物降解性等特点,壳聚糖智能水凝胶能够感知外界微小的物理化学刺激,如温度、pH、电场等并在响应过程中有显著的溶胀行为或响应性,壳聚糖水凝胶的研究已引起国内外学者的广泛关注.文章介绍了壳聚糖智能水凝胶的研究现状及其在药物缓释方面的应用,并对其发展前景进行了展望.Chitosan has good biocompatibility and biodegradation characteristics, Chitosan intelligent hy- drogel has remarkable stimulative responsibility （or swelling behavior） to tiny stimulus from environ- ment, such as temperature, pH, electric field, etc. The research about chitosan hydrogel had aroused the wide attentions of domestic and overseas scholars. The current research circumstance of the intelligent hydrogels was introduced in the paper, and application in drug release of the chitosan hydrogel were de- scribed. Its development in the future was predicted, too.

关 键 词：壳聚糖 智能水凝胶 药物缓释 

分 类 号：O636.1[理学—高分子化学]