头颈癌及颈淋巴结转移的分子影像学诊断  

DIAGNOSIS OF MOLECULAR IMAGING ON HEAD AND NECK CARCINOMA AND CERVICAL LYMPH NODE METASTASIS

作　　者：孙静涛[1] 张再兴[2] 张文军 杜彦霜 张东香[1] 刘蕊[1] 王铁钢 

机构地区：[1]河北省唐山市妇幼保健院放射科,063000 [2]河北联合大学附属医院耳鼻喉科 [3]唐山市工人医院PET/CT室 [4]石家庄市妇幼保健院功能科 [5]唐山市中医医院CT室

出　　处：《中国煤炭工业医学杂志》2013年第7期1049-1052,共4页Chinese Journal of Coal Industry Medicine

基　　金：2013年河北省卫生厅重点科技研究计划项目

摘　　要：目的探讨PET/CT显像、MRI、MSCT在头颈癌原发灶及颈部淋巴结转移中的诊断价值。方法选择2009年1月—2013年1月经手术或诊断取材病理证实的应用PET/CT显像诊断的130例头颈癌的患者,其中114例行MSCT、86例行MRI检查,分析三种检查方法在头颈癌诊断中各自的优势。结果对所有头颈癌原发灶诊断,PET/CT的敏感性、特异性、准确性明显高于MSCT、MRI,比较差异均有统计学意义(P<0.05),MSCT与MRI比较差异无统计学意义。对于甲状腺癌,MSCT高于MRI,比较差异有统计学意义(P<0.05)。对颈部淋巴结转移,PET/CT的敏感性明显高于MRI、MSCT,MRI高于MSCT,差异有统计学意义(P<0.05)。PET/CT、MRI特异性、准确性高于MSCT,差异有统计学意义(P<0.05)。PET/CT与MRI比较差异无统计学意义。结论 PET/CT是检出和准确诊断头颈癌及颈部淋巴结转移的最有效的分子影像学检查方法,对于临床制定治疗方案具有重要意义,但费用较高。MSCT在甲状腺癌的诊断上比MRI有一定优势,PET/CT、MRI对颈部淋巴结转移的测定相当,均优于MSCT。Objective To investigated the diagnostic value of PET/CT imaging,MRI,MSCT in head and neck carcinoma and neck lymph node metastasis.Methods The clinical data were analyzed retrospectively in 130 patients with head and neck carcinoma from January 2009 to January 2013.All cases were diagnosed by Positron emission tomography/computed tomography,114 patients received multi-slice spiral computed tomography,the other 86 cases received magnetic resonance imaging.Results On primary head and neck carcinoma lesion,PET/CT was significantly higher on diagnostic accuracy,sensitivity and specificity than that of MSCT and MRI,there were significant differences in three groups（P0.05）,but no significant differences between MSCT and MRI groups（P0.05）.On thyroid carcinoma,MSCT was higher than that of MRI,the difference was statistically significant;As for lymph node metastasis,the sensitivity of PET/CT was higher than that of MRI and MSCT,MRI higher than that of MSCT,there were also statistically significant difference（P0.05）,but no significant differences between PET/CT and MRI groups（P0.05）.Conclusions PET/CT is the most effective examination method on diagnosis of head and neck carcinoma and cervical lymph node metastasis.It maybe plays an important role in clinical treatment,but the cost is high.PET/CT and MRI has almost equivalent determination of cervical lymph node metastasis,both of them were better than MSCT,but MSCT has certain advantages in the diagnosis of thyroid carcinoma than that of MRI.

关 键 词：PET CT 显像头颈癌 颈淋巴结转移 多层螺旋X线计算机体层成像 核磁共振成像 

分 类 号：R814.4[医药卫生—影像医学与核医学]