醒脑静与纳洛酮联合氟马西尼治疗重度地西泮中毒  

Effect of Xingnaojing and naloxone combined with flumazenil on severe diazepam poisoning

作　　者：凤尔稳[1] 

机构地区：[1]安徽省黄山市人民医院急救中心,黄山245000

出　　处：《临床医学》2013年第5期26-27,共2页Clinical Medicine

摘　　要：目的观察醒脑静、纳洛酮联合氟马西尼治疗重度地西泮中毒的效果。方法将82例重度地西泮中毒患者随机分成三组:醒脑静、纳洛酮联合氟马西尼(Ⅰ)组28例,纳洛酮联合氟马西尼(Ⅱ)组30例,单用氟马西尼(Ⅲ)组24例,观察三组治疗后患者的清醒时间。结果三组清醒时间比较,Ⅰ组与Ⅱ组比较差异有统计学意义(P<0.05),Ⅰ、Ⅱ组与Ⅲ组比较差异有统计学意义(P<0.01)。结论醒脑静、纳洛酮联合氟马西尼治疗重度地西泮中毒催醒效果明显优于纳洛酮联合氟马西尼以及单用氟马西尼,具有比较理想的临床效果。Objective To observe the effect of Xingnaojing and naloxone combined with flumazenil on severediazepam poisoning.Methods Eighty-two cases of severe diazepam poisoning patients were randomly divided into three groups： the patients in group Ⅰ（28 cases） were given Xingnaojing and naloxone combined with flumazenil,while the patients in group Ⅱ（30 cases） were given naloxone combined with flumazenil,the patients in group Ⅲ（24 cases） were given flumazenil.The consciousness recovery time of the three groups were observed.Results The difference between group Ⅰ and group Ⅱ was statistically significant（P0.05）.The differences between group Ⅰ,group Ⅱ and group Ⅲ were statistically significant（P0.01）.Conclusion Xingnaojing and naloxone combined with flumazenil is significantly better than naloxone combined with flumazenil or only using flumazenil for acute diazepam poisoning.

关 键 词：地西泮中毒 醒脑静 纳洛酮 氟马西尼 

分 类 号：R595.3[医药卫生—内科学]