宫腔镜联合米非司酮预防围绝经期子宫内膜息肉复发的临床研究  被引量:8

Clinical investigation into prevention of endometrial polyp recurrence via hysteroscopical operation plus Mifepristone among perimenopausal women

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作  者:陈华萍[1] 曹培勇[1] 江宗群[1] 鲁娟[1] 周丽[1] 谢承芳[1] 

机构地区:[1]解放军第477医院妇产科,湖北襄阳441021

出  处:《临床军医杂志》2013年第6期587-588,共2页Clinical Journal of Medical Officers

摘  要:目的探讨宫腔镜手术联合米非司酮预防围绝经期子宫内膜息肉(EP)复发的可行性。方法 2008年6月—2012年2月在我院行宫腔镜EP切除术的围绝经期子宫内膜息肉患者共118例,按照宫腔镜息肉电切术后是否用药分为研究组60例,行宫腔镜下EP切除术,术后口服米非司酮12.5 mg,共3个月;对照组58例于宫腔镜下行EP切除术后不做任何处置。对两组患者进行复发和不良反应方面的随访观察。结果术后随访6个月,研究组与对照组比较,前者EP复发率明显低于后者(P<0.01),且不良反应轻。结论宫腔镜手术联合米非司酮治疗围绝经期子宫内膜息肉疗效肯定,不良反应轻,能够有效地预防EP复发。Objective To study the application of hysteroscopy combined with Mifepristone to the excision of recurrent endometrial polyps among perimenopausal women. Methods A total of 118 perimenopausal women with endometrial polyps treated between June 2008 and February 2012 were divided into trial group (n = 60 ) and control group (n = 58 ) according to whether Mifepristone was administered postoperatively or not. The trial group was given Mifepristone 12.5mg for 3 months after transcervical resection of polyp (TCRP) via hysteroscopy and the control group was given nothing after TCRP. The therapeutic outcomes were analyzed retro- spectively. Results The follow-up lasted for 6 months. The recurrent rate of the trial group was remarkably reduced when compared with that of the control group ( P 〈 0.01 ). Side effects were mild. Conclusion TCRP plus Mifepristone is effective on preventing endometrial polyps from recurrence.

关 键 词:子宫内膜息肉 宫腔镜 米非司酮 复发 

分 类 号:R711.74[医药卫生—妇产科学]

 

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