硫氮酮对冠心病心肌缺血的疗效观察  

Observations on therapeutic effects of diltiazem on coronary myocardiai ischemia

作　　者：邱建[1] 倪廷枢[1] 杨万军[1] 刘焕仪 

机构地区：[1]第三军医大学西南医院心内科,630038

出　　处：《第三军医大学学报》1991年第6期576-580,共5页Journal of Third Military Medical University

摘　　要：本文观察硫氮(?)酮(DT)135～240mg/d对26例冠心病心肌缺血的疗效,发现DT显著降低休息时,运动2、4,6 min、心率、血压和二项乘积,增加运动耐量,延迟运动诱发心绞痛,改善缺血性ST段下移和PEP/LVET,预防心绞痛发作。对冠心病合并高血压者疗效更明显,认为DT能改善心肌缺血,特别适用于冠心病伴高血压者。The therapeutic effects of diltiazem in the dosage of 135~240 mg/d on 26 cas-s with coronary myocardial ischemia were observed.It was found that diltiazem could markedly slow down tho heart rate and decrease the blood pressure of the patient when he was at rest and 2,4 and 6 minutes after he underwent exercise test.It could also increase exercise tolerance,delay an exercise-induced anginal attack,improve the ischemic depression of ST segment,and PEP/LVET.Eventually it could pievent the patient from anginal attacks.The therapeutic effects of diltiazem would be more apparent in those cases of myocardial ischemia accompanied with hypertension.

关 键 词：冠心病 心肌缺血 硫氮ZHOU酮 

分 类 号：R541.405[医药卫生—心血管疾病]