高脂蛋白血症中医分型与微循环、血液流变学改变的关系  

Relation between traditional Chinese medical types of hyperlipemia and microcirculation and blood viscosity

作　　者：高峻钰[1] 杨易灿[1] 夏天[1] 李满然 谢俊华[2] 刘正英[2] 

机构地区：[1]西京医院中医科 [2]西安交通大学卫生所

出　　处：《第四军医大学学报》1991年第1期12-14,共3页Journal of the Fourth Military Medical University

摘　　要：作者将63例高脂蛋白血症患者按中医辨证分为肝肾阴虚、肝郁气滞、肾虚及无症状4型,并对其微循环和血液流变学指标进行了检测.发现高脂患者血液粘度增高,低切、高切、血浆粘度分别为18.61±4.20mPas ′,6.25±0.65mPas′,1.99±0.32.正常对照组为14.77±0.70mPas′,5.89±0.30mPas′,1.65±0.10,相差均非常显著.微循环粒缓流,血管襻广泛渗出,出血,正常对照组分别为11％,2％,高脂组为53％,43％(P<0.01).同时各中医分型间也存在差异,肾虚组低切粘度为20.93mPas′,无症状组为16.5mPas′,肝肾阴虚、肝郁气滞分别为184mPas′,19.2mPas′.肾虚组100％患者微循环出现渗出、出血,无症状组出现率仅为28％,其余两组各为40％和48％,组间差异显著(P<0.05).说明高脂血症能引起微循环、血液流变学改变,改变程度却因不同证型而异.Sixty three patients with hypcrlipcmia were divided into 4 types by traditional Chinese medicine, namely kidney-asthenia ( KA), Yin-deficiency of liver and kidney (YDLK), depression of liver-energy (DLE) and No-symptom ( NS). Their microcirculation and blood viscosity were examined The blood viscosity in patients increased very significantly. Their low-shear rate, hight-shear rate and plasma viscosity were 18.61± 4.2 mPas. 6.25± 0.65 mPas and 1.99 ± 0.32, and in control group they were 14.77 ±0.7 mPas , 5.89±0.3 mPas and 1.65 1 0.1 (P<0.01) respectively. Finger nail microcirculation was variable too, 53% of patients showed incrcation of red blood cell aggregation in capillary and 43% of patients showed oo?ing and bleeding around the capillary loops. These were very significantly different comparing with control group, which were 11% and 2% respectively. On the other hand, the injury of different degrces was found in all the four groups of hypcrlipcmia patients. Blood viscosity on low shear rate was 20.93 mPas in KA group, 16.5 mPas ' in XS group, 18.4 mPas in YDLK group and 19.2 mPas in DLE group respectively. Bleeding around the capillary as found in 100% paticnls in KA group, only 28% in NS group, 40% patients in YDLK group and 48% in DLT group respectively. The difference is significient (P<0.05). The results indicate that hypcrlipcmia can alter microcirculation and blood viscosity. The degree of these changes is different in different types.

关 键 词：高脂蛋白血症 辨证分型 血液流变学 

分 类 号：R259.892[医药卫生—中西医结合]