生、蜜炙百部替换入方剂后化学成分研究  

Effect of Raw Instead of Processed Baibu on Chemical Constituents in Prescription

作　　者：陈晓霞[1] 魏熙婷[1] 邓仕任[1] 贾天柱[1] 

机构地区：[1]辽宁中医药大学,辽宁大连116600

出　　处：《广州化工》2013年第13期136-138,共3页GuangZhou Chemical Industry

基　　金：2010;2011年中医药行业科研专项项目(201107007)

摘　　要：建立了以ODS为色谱柱,甲醇-0.1%磷酸水梯度洗脱,在284 nm波长下同时测定小儿百部止咳糖浆中的黄芩苷、橙皮苷及芒果苷的含量方法。并且测定了以生百部替换蜜炙百部入方剂中上述三种成分的含量,结果发现炙百部入复方中黄芩苷、橙皮苷及芒果苷的含量均约2倍于生品入复方含量。可能是蜜炙百部入复方后,各种化学成分之间相互作用更能促进有效成分的溶出。The concentration of Baielin, hesperidin and Mangiferin in Xiaoerbaibuzhiketangjiang were separated and determined by RP - HPLC. The chromatographic conditions were chosen as follows ： the mobile phrase consisted of metha- nol, 0. 1% H3 PO4 - H2 O, the column was ODS, and the wavelength for detection of 284 nm. The concentration of Baic- lin, hesperidin and Mangiferin of Xiaoerbaibuzhiketangjiang raw Baibu instead of processed Baibu were detected and re- suits showed concentration of three components was about twice as much as in processed - Xiaoerbaibuzhiketangjiang. Maybe, processed Baibu can promote the dissolving- out ratio of active constituents.

关 键 词：生 炙百部 小儿百部止咳糖浆 化学成分 

分 类 号：R917[医药卫生—药物分析学]