经皮肺穿刺活检+组织培养在菌阴肺结核诊断中的价值  

Value of percutaneous needle biopsy and tissue culture in culture-negative pulmonary tuberculosis

作　　者：孟家晓 李品林 王建华 陈世浩 吴智龙 

机构地区：[1]佛山市第四人民医院放射科,广东528000

出　　处：《影像诊断与介入放射学》2013年第3期177-180,共4页Diagnostic Imaging & Interventional Radiology

基　　金：广东省佛山市科技发展专项资金项目(201008043)

摘　　要：目的探讨透视或CT导引下经皮肺穿刺在菌阴肺结核诊断中的应用价值。方法 87例临床诊断疑似菌阴肺结核的患者,CT平扫后增强扫描,在透视或CT引导下行经皮肺部病灶细针穿刺活检,活检组织分别送病理检查及结核分枝杆菌组织培养。结果 87例穿刺均取得活检组织,穿刺成功率达100%,病理诊断符合结核64例,穿刺标本组织培养出结核分枝杆菌43例;病理+组织培养诊断肺结核70例:准确性为80.5%,敏感性为95.9%,特异性为100%。结论在透视或CT导引下行经皮肺穿刺活检,获得病理及细菌学结果,是诊断菌阴肺结核的有较手段。Objective To assess the value of fluoroscopy or CT-guided percutaneous needle biopsy in culture-negative pulmonary tuberculosis （TB）. Methods After contrast-enhanced CT, 87 patients with suspected TB underwent fluoroscopyor CT- guided fine-needle aspiration （FNA） biopsy. Biopsy specimens were sent for pathological analysis and Mycobacterium TB tissue culture. Results FNA was successful on all 87 patients. Mycobacterium TB was confirmed histologically in 64 patients and by tissue culture in 43 patients with combined accuracy of 80.5%, sensitivity of 95.9%, and specificity of 100% in 70 patients. Conclusions Fluoroscopy or CT-guided pereutaneous FNA biopsy is effective for culture-negative TB.

关 键 词：菌阴肺结核 病理 组织培养 

分 类 号：R521[医药卫生—内科学]