斑蝥酸钠注射液致喉头水肿  

Laryngeal edema induced by disodium cantharidinate injection

作　　者：陈小蕾[1] 吴立强 赵青 

机构地区：[1]海南省中医院药学部,海南海口570203 [2]武警海南省总队医院,海南海口570203

出　　处：《中国药物应用与监测》2013年第3期183-184,共2页Chinese Journal of Drug Application and Monitoring

摘　　要：1例72岁男性患者,确诊为左肺腺癌7个月,既往有小牛血清去蛋白过敏史。治疗期间输入斑蝥酸钠注射液约30min,患者突然烦躁,急发憋闷、喉痒、发声嘶哑、吸气性呼吸困难,口唇明显发绀,三凹征阳性等。立即停止输入,给予氧气吸入,甲强龙、异丙嗪、葡萄糖酸钙抗过敏以及其他对症治疗,约20 min后,患者症状明显改善,口唇发绀及三凹征消失。One 72-year-old male patient was diagnosed with left lung adenocarcinoma 7 months ago.He had a history of deproteinised calf blood serum injection allergy.About 30 minutes after the disodium cantharidinate injection was used,the patient suddenly developed dysphoria,oppressed,throat itching,voice hoarse,inspiratory dyspnea,obvious lips hematocyanosis,three depression sign positive and so on.This medicine was immediately stopped.The patient received oxygen inhalation and the therapy of antianaphylaxis by methylprednisolone,promethazine hydrochloride injection,calcium gluconate and other treatments.After about 20 minutes,the symptoms improved obviously,lips hematocyanosis and three depression sign disappeared.

关 键 词：斑蝥酸钠注射液 喉头水肿 药品不良反应 

分 类 号：R595.3[医药卫生—内科学]