1749例住院新生儿TORCH感染调查与分析  

Investigation and analysis of TORCH infection of 1749 hospitalized neonates

作　　者：刘伟旗[1,2] 刘鹏飞[3] 冼璐桦[4] 

机构地区：[1]佛山市禅城区中心医院 [2]广东医学院附属佛山禅城医院检验科,广东佛山528031 [3]南方医科大学第三附属医院检验科,广东广州510630 [4]广东省人民医院/广东省医学科学院检验科,广东广州510080

出　　处：《国际检验医学杂志》2013年第11期1393-1394,共2页International Journal of Laboratory Medicine

摘　　要：目的了解广东地区新生儿TORCH感染状况及其与疾病的关系。方法随机采集广东省人民医院住院儿科新生儿1749例,采用酶联免疫吸附测定(ELISA)法检测TORCH-IgM抗体,450nm波长读取吸光度,以Cutoff值和ISR值判断结果。结果新生儿TORCH-IgM总阳性率为2.17%,巨细胞病毒(CMV)、风疹病毒(RV)、弓形虫(TOX)、单纯疱疹病毒(HSV)感染率分别为1.26%、0.57%、0.17%、0.17%。在新生儿TORCH感染中,发现男性新生儿TORCH-IgM阳性率为2.31%,高于女性新生儿的1.93%。38例TORCH感染新生儿高胆红素血症、肝功能损害、贫血、心功能损伤的发病率分别为57.89%、52.63%、39.47%、10.53%。结论加强对孕产妇进行TORCH-IgM孕前筛查宣传,减少新生儿TORCH感染,降低新生儿疾病的发生。Objective To understand the TORCH infection status of neonates in Guangdong region and its relationship with diseases.Methods 1 749 neonates hospitalized in the pediatrics department of Guangdong provincial people＇s hospital were randomly collected.TORCH IgM antibody was detected by enzyme-linked immunosorbent assay（ELISA） and the absorbance values were read at a wave-length of 450 nm.Result judgments were based on Cutoff values and ISR values.Results The total positive rate of TORCH IgM of neonates was 2.17%.The infection rates of CMV,RV,TOX,HSV were 1.26%,0.57%,0.17%,0.17%,respectively.In the neonatal TORCH infecion,TORCH IgM positive rate of 2.31% was found in male neonates,which was higher than that of 1.93% in female neonates.Incidences of hyperbilirubinemia,liver function lesion,anemia and heart function damage in 38 cases of neonatal TORCH infection were 57.89%,52.63%,39.47%,10.53%,respectively.Conclusion Progestational propaganda of TORCH IgM scanning in pregnant and lying-in women should be strengthened,and neonatal TORCH infection should be decreased,in order to lower the incidence of neonatal diseases.

关 键 词：新生儿 TORCH 感染 

分 类 号：R722.1[医药卫生—儿科]