康复新液口服与雾化吸入法治疗放射性口腔粘膜反应疗效观察  

The efficacy of oral Kangfuxin liquid combined with aerosolized inhalation of the liquid in prevention of acute radiation stomatitis

作　　者：李彩萍[1] 谭洁媚[1] 邓金笑[1] 李淑珍[1] 

机构地区：[1]江门市中心医院中山大学附属市江门医院,529030

出　　处：《国际医药卫生导报》2013年第13期1922-1924,共3页International Medicine and Health Guidance News

基　　金：江门市科技计划项目（2011105）

摘　　要：目的 比较康复新液口服与雾化吸入法在头颈部肿瘤放疗中防治急性放射性口腔粘膜反应的临床效果.方法 将200例接受放射治疗的头颈部肿瘤患者随机分为A组（口服组100例）和B组（雾化组100例）.A组采用口服法,3次/d,缓慢吞服；B组采用雾化吸入法,2次/d.两组患者均于放疗开始时使用至放疗结束.结果 A组2～3级放射性粘膜炎发生率为19％,B组2～3级放射性粘膜炎发生率为33％,差异有统计学意义（x2=5.09,P＜0.05）.结论 康复新液口服及雾化吸入法均能减轻及缩短口腔粘膜急性放疗反应的程度及时间,单用口服法优于雾化吸入法,口服法加雾化吸入法相结合效果更好,值得临床推荐使用.Objective To compare the efficacy of oral Kangfuxin liquid with that of aerosolized inhalation of the liquid in the prevention of acute radiation stomatitis in patients with head and neck tumors undergoing radiation therapy.Methods 200 patients with head and neck cancer were randomly divided into group A （oral group,100 patients） and group B （inhalation group,100 patients）.Group A received oral Kangfuxin liquid 3 times daily,while group B received aerosolized inhalation of the liquid twice daily.The treatment lasted during the whole radiotherapy.Results The incidence rate of grades 2 to 3 radiation stomatitis was lower in group A than in group B （19% in group A and 33% in group B,x2=5.09,P〈0.05）; there was a significant difference between the two groups.Conclusions Both oral Kangfuxin liquid and aerosolized inhalation of the liquid can reduce the severity of acute oral mucosal radiation reaction and shorten the duration of therapy.Oral Kangfuxin is better than inhalation.Combination therapy is more effective and is worth popularizing clinically.

关 键 词：康复新液 口服 雾化吸入 放射性口腔粘膜反应 放射治疗 疗效 

分 类 号：R473.73[医药卫生—护理学]