上尿路尿酸结石的成分和代谢的分析  

Analysis of Chemical Composition of Uric Acid Stones in Upper Urinary Tract and Metabolic Disturbance

作　　者：苏海龙 谢春文 周兴[2] 

机构地区：[1]广东省佛山市顺德区勒流医院,广东佛山528322 [2]广州医学院附属医院

出　　处：《中国医学创新》2013年第19期84-86,共3页Medical Innovation of China

基　　金：广东省佛山市卫生局医学科研基金项目(编号:2010417)

摘　　要：目的:分析顺德勒流地区上尿路尿酸结石成分与代谢异常的关系,探讨尿酸结石形成的代谢性因素,为临床预防和治疗上尿路尿酸结石提供新的依据。方法:252例上尿路结石患者中83例尿酸结石,其中64例完整血生化及24h尿分析结果。结果:纯尿酸成分结石占尿酸结石总数的34.9%(29/83),混合成分结石占65.1%(54/83)。64例有完整血生化及24h尿分析结果患者中代谢异常52例(81.3%),两种以上代谢异常所占比例为43.8%(28/64)。56例随访10～42个月,平均20个月。无泌尿系结石复发32例,复发24例,无复发组代谢无异常9例,复发组1例(P<0.05)。结论:确定尿酸结石成分及患者的代谢评价对上尿路尿酸结石的成因、治疗和预防有重要的临床意义。Objective：To explore the metabolic factors of formation of uric acid stones in upper urinary tract in ShunDe LeLiu area,by analysis uric acid calculi ingredient on its relationship with metabolic abnormalities,for providing a new basis of prevention and treatment of uric acid calculi in upper urinary.Method：83 uric acid stone patients of 252 upper urinary tract stone patients who had undergone analysis of stone composition,64 of them pentire blood biochemistry 24-hurine analysis.Result：Pure uric acid calculus account for 34.9%（29/83）and mix component calculus account for 65.1% （54/83）. Metabolic disturbance was found in 52（81.3%）of 64 patients with entire blood biochemistry results and 24-h urine analysis results.More than one kinds of metabolic disturbances account for 43.8%（28/64）.56 cases were followed up for an average of 20 months（range,10-42 months）;of them 32 cases were stone-free,and 24 cases had stone recurence.The number of patients without metabolic disturbance was higher in stone-free group （9 cases）than that in stone recurence group（1 cases）（P ＆lt;0.05）.Conclusions：Uric acid stone composition analysis and metabolic evaluation are very important in finding the causes and in treating and preventing uric acid stones in upper urinary tract.

关 键 词：上尿路 尿酸结石 结石成分 代谢异常 

分 类 号：R691.4[医药卫生—泌尿科学]