子宫螺旋动脉血流参数结合血清CA125预测先兆流产结局  

Uterine spiral artery hemodynamics parameters combined with serum CA125 in predicting the outcome of threatened abortion

作　　者：陈海燕[1] 刘江泽[1] 胡小韦[1] 殷红霞[1] 

机构地区：[1]玉林市第一人民医院超声科,广西玉林537000

出　　处：《华夏医学》2013年第3期454-456,共3页Acta Medicinae Sinica

摘　　要：目的:应用彩色多普勒超声(CDFI)监测先兆流产孕妇子宫螺旋动脉(USA)血流参数及血清糖原抗原(CA125)变化,探讨其临床应用价值。方法:应用CDFI检测正常早孕组(A组)、先兆流产保胎成功组(B组)、先兆流产保胎失败组(C组)各50例USA的血流参数及血清CA125结果进行分析。结果:C组与A组、B组比较USA的血流参数及血清CA125有显著差异(P<0.05),RI、CA125有明显增高,PSV、EDV明显降低(P<0.05);RI>0.56结合血清CA125>80U/L预测妊娠结局比单一使用RI>0.56或血清CA125>80U/L的特异度和诊断指数要高。结论:应用CDFI测定USA血流参数及血清CA125预测先兆流产妊娠结局有重要的应用价值。Objective. To discuss the clinical significance through the application of color doppler flow imaging （CDFI） to monitoring the changes of the blood flow parameters of the uterine spiral artery （USA） and serum CA125 in women with threatened abortions. Methods. The early normal pregnant women detected with CDFI were selected as Group A （50 cases）, Group B （50 cases） was for the threatened abortion women but succeeded in maintaining pregnancy, while Group C （50 cases） was for the threatened abortion women but failed in maintaining pregnancy. The the blood flow pa- rameters of USA and serum CA125 of the subjects in three groups were analyzed. Results： Com- pared Group C with Group A and B, there were significant differences in the blood flow parameters of USA and serum CA125 （P〈0. 05） ; RI and CA125 increased obviously, while PSV and EDV decreased remarkably （P〈0.05）. The specificity and diagnostic index were higher in predicting pregnant outcomes by application of RI larger than 0.56 combined with serum CA125〉80 U/L than by applying only RI〉0. 56 larger than or only applying serum CA125-80 U/L. Conclusion： The combined applications of hemodynamics parameters of USA and serum CA125 have important values in predicting pregnant outcomes of threatened abortion.

关 键 词：先兆流产 子宫螺旋动脉 CA125 

分 类 号：R714.21[医药卫生—妇产科学]