伊马替尼治疗慢性髓细胞性白血病不良反应的观察及护理  

Observation and nursing of adverse reactions in chronic myelocytic leukemia patients receiving ima- tinib therapy

作　　者：卢玲[1] 赵素芳[1] 张日[1] 

机构地区：[1]苏州大学附属第一医院江苏省血液研究所卫生部血栓与止血重点实验室,215006

出　　处：《中国实用护理杂志》2013年第19期33-35,共3页Chinese Journal of Practical Nursing

摘　　要：目的探讨伊马替尼治疗慢性髓细胞性白血病不良反应的观察及护理体会。方法对193例使用伊马替尼治疗慢性髓细胞性白血病慢性期的患者，观察用药不良反应并对之进行观察、记录和治疗护理。结果193例中，超过60％患者出现不良反应，表现为恶心、呕吐、纳差、腹泻等胃肠道反应54％；肌肉、骨骼疼痛22％；皮疹7％；水肿、体质量增加65％。经过有效治疗和护理，均获得完全或部分缓解。结论在伊马替尼治疗慢性髓细胞性白血病慢性期的过程中，密切观察可能的不良反应，积极治疗和护理有助于患者坚持用药，达到长期缓解。Objective To discuss the observation and nursing of adverse reactions in chronic myelo- cytic leukemia patients receiving imatinib therapy. Methods Adverse reactions were observed and recorded in 193 chronic phase myelocytic leukemia patients who received imatinib therapy, and correspond- ing treatment and nursing were given to them. Results Among 193 patients, more than 60% of patients had adverse reactions, of which, 54% of patients showed gastrointestinal adverse reactions including nausea, vom- iting, anepithymia and diarrhea; 22% of them had muscle and bone pain; 7% had rash; 65% got edema. After proper treatment and nursing, all adverse effects obtained satisfactory remission. Conclusions During the treatment course of chronic myelocytic leukemia patients using imatinib, careful observation of any possible adverse reactions ,and giving corresponding treatment and nursing can facilitate good compliance and long- term remission of patients.

关 键 词：伊马替尼 慢性髓细胞性白血病 不良反应 护理 

分 类 号：R473.73[医药卫生—护理学]