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作 者:代雪梅[1] 刘丹[1] 刘凤[1] 沈霞蔚[1] 肖醉萱[1]
机构地区:[1]长江大学附属第一医院内分泌科,湖北荆州434000
出 处:《现代生物医学进展》2013年第17期3316-3319,共4页Progress in Modern Biomedicine
摘 要:目的:探讨2型糖尿病患者发生下肢血管病变的危险因素。方法:回顾性分析我院2009年12月~2011年12月收治的98例2型糖尿病患者的临床资料,通过彩色多普勒超声检查其下肢血管,按下肢血管有无病变将其分为单纯2型糖尿病租和2型糖尿病合并下肢血管病变组,通过非条件Logistic回归分析导致2型糖尿病患者发生下肢血管病变的危险因素。结果:彩色多普勒超声检查结果显示,98例2型糖尿病患者中,61例发生不同程度下肢血管病变,占62.24%。与单纯2型糖尿病组比较,下肢血管病变组患者年龄、病程、收缩压及低密度脂蛋白胆固醇的差异均有统计学意义(P<0.05),经非条件Logistic回归分析,患者的年龄、病程、SBP及LDL-L是下肢血管病变的独立危险因素(P<0.05)。结论:2型糖尿病患者下肢血管病变的发生与患者的年龄、病程、血压及血脂情况密切相关。Objective: To explore the occurrence rate of lower extremity angiopathy in type 2 diabetes and risk factors.Methods: Doppler ultrasound examination were performed on 98 cases with type 2 diabetes.The differences of clinical indexes were compared between type 2 diabetes group and lower extremity angiopathy group by retrospective analysis.The risk factors of lower extremity angiopathy in type 2 diabetes were analyzed by Logistic regression.Results: 61 cases(62.24%) occurred lower extremity angiopathy.Compared with type 2 diabetes group,the age,course of disease,SBP and LDL-C showed statistical significance in lower extremity angiopathy group(P0.05).The age,course of disease,SBP and LDL-C were independent risk factors of lower extremity angiopathy in type 2 diabetes(P0.05).Conclusion: Doppler ultrasound can find location and severity of lesions of lower extremity angiopathy in type 2 diabetes.The related factors of lower extremity angiopathy are age,course of disease,blood pressure and cholesterol level.
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