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作 者:周建伟[1] 李静[2] 赵菁菁[3] 谢慧君[3] 王敏[3] WANG Fang
机构地区:[1]四川省中医药科学院 [2]四川大学华西医院循证医学与临床流行病学中心 [3]四川省中医药科学院中医研究所
出 处:《World Journal of Acupuncture-Moxibustion》2013年第2期41-47,共7页世界针灸杂志(英文版)
基 金:Supported by Sichuan Science and Technology Support Program: 2011 SZ0253
摘 要:Objective To evaluate the efficacy and safety of scalp acupuncture in the treatment of ischemic stroke. Methods The method recommended in the Cochrane Collaboration was used for the systematic evaluation of the randomized controlled trials (RCTs) of scalp acupuncture in the treatment of ischemic stroke. Results One thousand three hundred and ninety-five cases from 13 papers in Chinese version were in compliance with the inclusive criteria and all of them were the low-quality trials. The results of the included 5 trials in Meta analysis indicated that the efficacy of scalp acupuncture was superior to medication in the treatment of ischemic stroke (RR=1.27, 95% CI 1.06, 1.51). The results of 3 trials in Meta analysis suggested that the recovery in the nerve function defect of the patients with ischemic stroke treated with scalp acupuncture was apparent as compared with medication (WMD = -2.96, 95% C1-4.00, -1.92). The results of 5 trials in Meta analysis showed that the efficacy of scalp acupuncture on ischemic stroke was potentially superior to body acupuncture (RR=I.10, 95% CI 0.93, 1.28). Conclusion It is seen in the Meta analysis results of the included 13 RCTs that scalp acupuncture achieves the definite efficacy on ischemic stroke. Due to the limitation of the inclusive numbers and quality of the research, especially the lack of long-term indices, the conclusion reliability of this research is relatively low. Hence, it is required much more evidences for a further confirmation from the large scale and multiple central RCTs with high quality and intrinsic authenticity.目的:评价头针疗法治疗缺血性中风病的疗效和安全性。方法:对头针疗法治疗缺血性中风病的随机对照试验(RCT)按Cochrane协作网推荐的方法进行系统评价。结果:13篇中文文献1395例患者满足纳入标准,均为低质量试验。纳入的5个试验Meta分析结果提示头针疗法治疗缺血性中风病的疗效优于药物治疗(RR=1.27,95% CI 1.06,1.51);3个试验Meta分析结果提示头针疗法对缺血性中风病患者神经功能缺损的恢复较药物治疗明显(WMD=-2.96,95%CI -4.00,-1.92);5个试验Meta分析结果提示头针疗法治疗缺血性中风病的疗效可能优于体针治疗(RR=1.10,95% CI 0.93,1.28)。结论:从纳入的13个RCTs的Meta分析结果看,头针疗法治疗缺血性中风病疗效肯定。由于纳入研究数量和质量上的缺陷,尤其是缺乏远期指标,使本研究结论的可靠程度较低,因此需更多高质量、内在真实性好的大规模、多中心的RCT试验证据进一步证实。
关 键 词:ischemic stroke cerebral infarction scalp acupuncture therapy evidence-based medicine Meta analysis
分 类 号:R246[医药卫生—针灸推拿学]
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