早产胎膜早破300例临床分析  

Clinical analysis on 300 cases with preterm premature rupture of membrane

作　　者：朱庆辉[1] 周荣向[1] 喻莉莉[1] 

机构地区：[1]广州解放军第421医院妇产科,广东广州510318

出　　处：《中国妇幼保健》2013年第19期3093-3095,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨胎膜早破(PROM)的原因、治疗方法、结局。方法:对2007年12月～2011年12月300例胎膜早破的住院分娩的产妇资料进行回顾性研究。结果:生殖道感染和胎位异常是胎膜早破发生的主要诱因;利托君、硫酸镁抑制宫缩治疗延长妊娠时间;糖皮质激素的应用减少了肺透明膜病变的发生率;血清C反应蛋白(CRP)的监测是抗生素应用时间、效果的指标;剖宫产指征主要是胎儿窘迫。结论:早产胎膜早破发生的原因与胎位异常及生殖道感染关系密切;抑制宫缩延长妊娠时间及抗生素、糖皮质激素的应用明显改善新生儿结局;分娩方式、时机主要依据胎儿宫内情况决定。Objective： To explore the causes,treatment and outcome of premature rupture of membrane（PROM）.Methods： The data of 300 pregnant women with PROM who gave birth to their babies from December 2007 to December 2011 were studied retrospectively.Results： Reproductive tract infection and abnormal fetal position were main causes of PROM;ritodrine and magnesium sulfate could inhibit uterine contraction and prolong pregnancy time;application of corticosteroids reduced the incidence rate of pulmonary hyaline membrane disease;serum C-reactive protein（CRP） monitoring was a index of application time and effect of antibiotics;fetal distress was the main indication of cesarean section.Conclusion： The occurrence of PROM is closely related to abnormal fetal position and reproductive tract infection;inhibiting uterine contraction,prolonging pregnancy time,applications of antibiotics and glucocorticoids can obviously improve neonatal outcome;delivery modes and time mainly depend on intrauterine situations of fetus.

关 键 词：早产 胎膜早破 原因 治疗方法 结局 

分 类 号：R714.21[医药卫生—妇产科学]