糠酸莫米松鼻喷剂对表现为上气道咳嗽综合征的儿童慢性鼻-鼻窦炎的治疗作用  

Curative effect of mometasone furoate nasal spray on upper airway cough syndrome in children with chronic rhinosinusitis

作　　者：朱学伟[1] 孙宇新[1] 

机构地区：[1]吉林大学中日联谊医院耳鼻咽喉头颈外科,吉林长春130033

出　　处：《中国妇幼保健》2013年第19期3183-3184,共2页Maternal and Child Health Care of China

基　　金：吉林省卫生厅科技项目〔3D511APl3430〕;吉林大学种子基金〔450060481351〕

摘　　要：目的:观察糠酸莫米松鼻喷雾剂治疗表现为上气道咳嗽综合征的儿童慢性鼻-鼻窦炎的效果。方法:对48例表现为上气道咳嗽综合征的慢性鼻-鼻窦炎的患儿,用糠酸莫米松鼻喷雾剂进行治疗,观察治疗前后症状和体征总评分的改变,并对相关不良反应进行分析。结果:采用糠酸莫米松鼻喷雾剂治疗表现为上气道咳嗽综合征的慢性鼻—鼻窦炎患儿,治疗前咳嗽症状和鼻内镜检查评分平均为(3.02±1.61)分及(5.80±2.00)分;治疗3周后咳嗽症状和鼻内镜检查评分为(1.20±0.83)分及(2.01±1.19)分;治疗2个月后症状和体征总评分平均为(0.61±0.45)分及(1.38±0.89)分。治疗前与治疗后症状和体征总评分比较,差异有统计学意义(P<0.01)。结论:糠酸莫米松鼻喷剂对表现为上气道咳嗽综合征的儿童慢性鼻-鼻窦炎有一定疗效,其安全性及远期疗效值得进一步深入探讨。Objective： To observe the curative effect of mometasone furoate nasal spray on upper airway cough syndrome in children with chronic rhinosinusitis.Methods： Mometasone furoate nasal spray was used to treat upper airway cough syndrome in 48 children with chronic rhinosinusitis;the symptoms before and after treatment and the change of total score of signs were observed,and the related adverse reactions were analyzed.Results： The scores of cough symptom and endoscopy before treatment were（3.02 ± 1.61） and（5.80 ± 2.00）,respectively;the scores of cough symptom and endoscopy at three weeks after treatment were（1.20 ± 0.83） and（2.01 ± 1.19）,respectively;the total scores of symptoms and signs at two months after treatment were（0.61 ± 0.45） and（1.38 ± 0.89） on average.There were statistically significant differences in the total scores of symptoms and signs between before and after treatment（P 0.01）.Conclusion： Mometasone furoate nasal spray has a certain curative effect on upper airway cough syndrome in children with chronic rhinosinusitis,the safety and long-term curative effect need further studies.

关 键 词：儿童 上气道咳嗽综合征 咳嗽 慢性鼻-鼻窦炎 糠酸莫米松 

分 类 号：R725.6[医药卫生—儿科]