人血丙种球蛋白和甲强龙联合冲击治疗对于流行性乙型脑炎远期疗效观察  

Long-term effect of combination treatment of IVIG and methylprednisolone in ictus treatment of children with severe japanese encephalitis

作　　者：卜笑松[1] 吴德[1] 卢晓妹[1] 许晓燕[1] 杨李[1] 唐久来[1] 

机构地区：[1]安徽医科大学第一附属医院小儿神经康复中心,合肥230022

出　　处：《安徽医学》2013年第1期3-5,共3页Anhui Medical Journal

摘　　要：目的研究人血丙种球蛋白和甲强龙联合冲击治疗对流行性乙型脑炎的远期疗效。方法 89例重度乙脑患儿,随机分为治疗组45例,常规治疗基础上,加用丙球加甲强龙联合治疗7 d,1周后,同剂量再给予治疗3 d;对照组44例,常规治疗基础上加甲强龙1周。观察1、2、3周后的治疗效果、复发情况,以及6个月后的后遗症发生率。结果治疗组总有效率明显高于对照组;治疗组复发率和后遗症发生率明显小于对照组。结论丙球结合激素治疗,对于乙脑的近期及远期疗效均较好。Objective To study the long-term effect of combination treatment of IVIG and methylprednisolone in the ictus treatment of children with severe Japanese encephalitis.Methods Eighty-nine patients were divided into 2 groups： treatment group and control group.Treatment group was treated with IVIG and methylprednisolone based on conventional treatment and control group was treated with methylprednisolone based on conventional treatment.The curative effect of two groups was evaluated after first second and third week.Sequel incidence was assessed after half a year.Results Total effective rate of treatment group was higher than that of control group.Recurrence rate and sequelae of treatment group were less than those of control group.Conclusion Long-term effect of combination treatment of IVIG and methylprednisolone in the ictus treatment of children with severe Japanese encephalitis is satisfactory.

关 键 词：脑炎 流行性 甲强龙 人血丙种球蛋白 

分 类 号：R725.6[医药卫生—儿科]