不同治疗方案对急性胆源性胰腺炎患者炎症因子及医疗负担的影响  

The effect of different therapeutic schemes for acute biliary pancreatitis patients with inflammatory cytokines and medical burden

作　　者：刘东涛[1] 罗春梅[1] 李兵[1] 陈智敏[1] 韩强[1] 

机构地区：[1]四川省崇州市人民医院外科,611230

出　　处：《检验医学与临床》2013年第13期1662-1663,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨不同治疗方案对急性胆源性胰腺炎患者炎症因子及医疗负担的影响。方法以2009年7月至2012年7月收治的急性胆源性胰腺炎68例为研究对象,随机分为对照组和观察组,观察组早期使用介入治疗,对照组行常规治疗方案。比较两组患者临床疗效、炎性因子水平及医疗负担的差异。结果观察组患者在腹痛缓解时间、血淀粉酶转阴时间及平均住院时间方面皆少于对照组,IL-6、IL-12及TNF-α水平均低于对照组,在医疗负担方面轻于对照组,其差异皆有统计学意义(P<0.05)。结论对急性胆源性胰腺炎患者早期使用介入治疗方法可收到满意的临床效果,降低体内炎性因子水平,降低患者的医疗负担。Objective To explore the effect of different therapeutic schemes for acute biliary pancreatitis patients with inflammatory cytokines and medical burden. Methods From July 2009 to July 2012,the hospital treated 68 cases of acute biliary pancreatitis as the research object, randomly divided into control group and observation group. The observation group was treated with interventional therapy in early time and control group was treated with traditional therapy. Comparison of the difference between the two groups of patients with clinical effect, the lev- els of inflammatory factors and medical burden. Results In the observation group, abdominal pain relief time, recovery time of serum amylase and the average hospitalization time was less than the control group;IL-6, IL-12 and TNF- a levels were lower than the control group;The medical burden was lighter than the control group,the difference was statistically significant（P〈0.05）. Conclusion Patients with acute biliary pancreatitis using interventional therapy in early time can achieve satisfactory clinical effect,which also can reduce the level of inflammatory factors in vivo and the medical burden of patients.

关 键 词：急性胆源性胰腺炎 介入治疗 医疗负担 

分 类 号：R657.51[医药卫生—外科学]