科学合理应用心脏诊断标志物  

Scientific and rational application of diagnostic markers for cardiovascular disease

作　　者：王传新[1] 邹雄[1] 

机构地区：[1]山东大学齐鲁医院检验科,济南250012

出　　处：《中华检验医学杂志》2013年第6期481-484,共4页Chinese Journal of Laboratory Medicine

摘　　要：科学合理的应用诊断标志物，对心血管疾病的早期发现和指导临床治疗具有重要意义。心肌特异性肌钙蛋白的出现及其高敏检测方法的发展使得急性心肌梗死的早期无创性诊断成为可能，利钠肽用于诊断心力衰竭更是心脏标志物发展史中的亮点。随着新方法学研究的不断深入，可能会发现更多具有潜力的新型早期标志物和疾病风险预测因子，在为心血管疾病的早期诊断和治疗带来新的发展前景的同时，也为临床医师和检验工作者带来更多的挑战。The scientific and rational application of diagnostic marker is very important significant in the early detection and treatment of cardiovascular diseases. The emergence of cardiac-specific troponin and the development of high assays make it possible for early noninvasive diagnosis of acute myocardial infarction. The Natriuretic peptide used for the diagnosis of heart failure is a new cornerstone in the history of cardiac markers development. The future trends in new methodology development may find more potential new early markers and predictive factors, which could bring in new prospects for the early diagnosis and treatment of cardiovascular diseases, but also more challenges for clinicians and laboratory physicians.

关 键 词：心血管疾病 早期诊断 生物学标记 

分 类 号：R511.7[医药卫生—内科学]