硫辛酸片联合甲钴胺片治疗糖尿病周围神经病变56例  

Lipoic acid tablets combined with methylcobalamin tablets in treatment of 56 patients with diabetic peripheral neuropathy

作　　者：朱咏瑶 钟翠琼 刘勤发[1] 刘枘岢[1] 周敏华[1] 

机构地区：[1]广东省东莞市石龙人民医院内分泌科,广东东莞523326

出　　处：《中国医药科学》2013年第14期65-65,81,共2页China Medicine And Pharmacy

摘　　要：目的探讨硫辛酸片联合甲钴胺片治疗糖尿病周围神经病变的临床疗效。方法 112例糖尿病周围神经病变患者,随机分为观察组和对照组,对照组:饮食控制、常规降血糖,并采用甲钴胺片治疗。观察组:在对照组用药方式的基础上,加用硫辛酸片治疗。结果观察组总有效率为89.29%,高于对照组的71.43%,差异具有统计学意义(P<0.05)。结论硫辛酸片联合甲钴胺治疗糖尿病周围神经病变患者疗效佳。Objective To investigate the clinical efficacy of lipoic acid tablets combined Methylcobalamin tablets in the treatment of diabetic peripheral neuropathy. Methods 112 patients with diabetic peripheral neuropathy were randomly divided into the observation group and the control group.The control group received diet control,conventional blood sugar decrease and Methyleobalamin tablets treatment.The observation group received additional lipoic acid tablets on the basis of the control group. Results The total effective rate of the observation group was 89.29%,which was higher than the 71.43% of the control group,with significant difference （P 〈 0.05）. Conclusion Lipoic acid tablets combined with mecobalamin are effective in the treatment of patients with diabetic peripheral neuropathy.

关 键 词：硫辛酸片 甲钴胺片 糖尿病周围神经病变 

分 类 号：R587.2[医药卫生—内分泌]