妊娠继发嗜血细胞综合征1例并文献复习  

One case of pregnancy complicated with hemophagocytic syndrome and literature review

作　　者：郑转珍[1] 乔振华[1] 杨林花[1] 姜波[1] 王云鹏[1] 李阳[1] 

机构地区：[1]山西医科大学第二医院血液科,山西太原030001

出　　处：《中国医药科学》2013年第14期146-147,共2页China Medicine And Pharmacy

摘　　要：嗜血细胞综合征在临床中为少见病,多继发于病毒感染,继发于妊娠的少见。本研究报道了1例妊娠继发嗜血细胞综合征,在发病初期以粒细胞缺乏、骨髓感染为主要表现,之后逐渐出现三系全血细胞减少、甘油三酯升高、纤维蛋白原下降、血清铁蛋白升高、NK细胞缺乏;骨髓嗜血细胞现象。目前该病在临床工作中的诊断还存在一定的难度,而且本病进展迅速,病情凶险,病死率高,又无特效治疗,因此临床医生应提高对该病的认识,以尽早诊断,改善预后。Hemophagocytic lymphohistiocytosis was a rare disease in clinical practice and often caused by viral infection,but secondary to pregnancy was rare.This paper reports 1 case of pregnancy complicated with hemophagocytic syndrome.In the early onset,the main clinical manifestation was severe infection in bone marrow and neutropenic,then gradually appeared pancytopenia,elevated triglycerides,fibrinogen decreased,increased serum ferritin,NK cell deficiency and large amount of hemophagocytosis in bone marrow.The diagnosis is full of difficulty and the disease progress rapidly.It is dangerous and the mortality is high.There has no specific treatment.Clinicians should improve the understanding of this disease in order to make an early diagnosis to improve prognosis.

关 键 词：妊娠 败血症 嗜血细胞综合征 

分 类 号：R711[医药卫生—妇产科学]