脑血管狭窄的无创性诊断研究现状  

Noninvasive diagnosis of cerebral vascular stenosis

作　　者：祁小龙[1] 陈罗蔓[1] 范国鑫[1] 杨长青[2] 

机构地区：[1]同济大学医学院,上海200092 [2]上海市同济医院消化疾病研究所,上海200065

出　　处：《医学影像学杂志》2013年第7期1119-1122,共4页Journal of Medical Imaging

基　　金：国家自然科学基金(81070343);上海市优秀学科带头人计划(08×D14045);上海市科技创新行动计划(12431901002)

摘　　要：脑血管狭窄是引起缺血性脑卒中发作的主要原因,是威胁人类生命安全的三大杀手之一。目前诊断脑血管狭窄的"金标准"为脑动脉造影,但因其有创性且缺乏功能性判断指标,故在临床应用中受到一定限制。近年来,多种无创性成像技术为脑血管狭窄的诊断提供了新的途径,在一定程度上弥补了脑动脉造影的技术缺陷。本文就此方面的研究现状作一综述。Cerebral vascular stenosis is the main cause of the onset of ischemic stroke and one of the three major killers of human safety. At present, digital subtraction angiography （DSA）, as the ＂golden standard＂ of cerebral vascular stenosis, is limited to a certain extent in its clinical applications due to the invasiveness and lack of functional index. In recent years, variable noninvasive imaging technologies provides new strategies for the diagnosis of cerebral vascular stenosis, such as Doppler ultrasound （DUS）, computed tomographic angiography （CTA）, magnetic resonance angiography （MRA）, etc. However, currently available noninvasive assessments have merely the ability to evaluate the anatomically stenosis. Therefore, it is urgently needed to find a noninvasive assessment to evaluate the cerebral functional ischemia. This review shows the diverse approaches in the determination of cerebral vascular stenosis with regard to their merits and defects.

关 键 词：脑血管 硬化狭窄 无创 影像诊断 

分 类 号：R713.1[医药卫生—妇产科学]