超声清创联合智能负压创伤疗法治疗糖尿病足溃疡的临床研究  

Clinical research of ultrasonic debridement and intelligence negative-pressure wound therapy for diabetic foot ulcers

作　　者：颜晓东[1] 徐国玲[1] 钟玫[1] 黄秀禄[1] 谭小燕[1] 农月稠[1] 

机构地区：[1]广西壮族自治区人民医院内分泌代谢科糖尿病足病治疗中心,南宁530021

出　　处：《中国医师进修杂志》2013年第19期10-12,共3页Chinese Journal of Postgraduates of Medicine

基　　金：基金项目：广西壮族自治区卫生厅重点科研课题（桂卫Z200811）

摘　　要：目的探讨超声清创联合智能负压创伤疗法在糖尿病足溃疡Wagner分级2～3级治疗中的有效性和安全性。方法将80例糖尿病足溃疡Wagner2～3级患者根据治疗方案分为超声清创联合智能负压创伤疗法组（负压组，53例）和常规治疗组（常规组，27例）。两组均辅以控制血糖及血压、抗凝、抗感染及对症支持治疗。比较两组疗效及并发症。结果负压组愈合29例，显效14例，有效7例，无效3例，总有效率为94．34％（50，53）；常规组愈合7例，显效8例，有效6例，无效6例，总有效率为77．78％（21，27），两组总有效率比较差异有统计学意义（P〈0．05）。负压组超声清创过程中发生疼痛9例，血红蛋白下降1例，无其他并发症发生。结论超声清创后再对创面给予智能负压创伤疗法在治疗糖尿病足溃疡Wagner2—3级中显示良好的有效性和安全性。Objective To evaluate the efficiency and safety of ultrasonic debridement therapy （UDT） and intelligence negative-pressure wound therapy（INPWT） for diabetic foot ulcers with Wagner 2 - 3 degree. Methods Eighty patients with diabetic foot ulcers with Wagner 2 - 3 degree were divided into two groups according to the treatment method . The UDT and INPWT group （INPWT group） had 53 cases. Routine treatment group（routine group） had 27 cases. Both groups were given blood sugar and blood pressure control, anticoagulatian, anti-infection and supportive treatment. The efficiency and complications were compared between two groups. Results In INPWT group, 29 cases were healed, 14 cases showed obvious effectiveness, 7 eases were effective and 3 cases were inefficacy. The total effective rate was 94.34% （50/53）. For routine group, they were 7, 8, 6, 6 cases and 77.78% （21/27） respectively. The total effective rate between two groups had significant difference （P 〈0.05）. Pain was found in 9 cases and hemoglobin decreased in 1 case in INPWT group. Conclusion INPWT after UDT for diabetic foot ulcers with Wagner 2-3 degree shows a good efficiency and safety.

关 键 词：糖尿病足 血气监测 经皮 超声清创 智能负压创伤治疗 

分 类 号：R587.2[医药卫生—内分泌]