震动感觉阈值对诊断早期糖尿病周围神经病变的临床意义  

Clinical significance of VPT in early diagnosis of diabetic peripheral neuropathy

作　　者：刘美萍 陈敏 胡湘明 何霞 宋俊华 尹代婵 周康 陈珊 

机构地区：[1]长沙市第四人民医院,湖南长沙410006

出　　处：《现代医药卫生》2013年第11期1604-1605,共2页Journal of Modern Medicine & Health

基　　金：湖南省卫生厅科学基金资助项目(B2008-082)

摘　　要：目的探讨震动感觉阈值(VPT)检测在新发2型糖尿病周围神经病变(DPN)筛查中的应用效果。方法对新确诊的50例无足麻木、灼痛、刺痛等感觉的2型糖尿病患者分别分组进行VPT检测及神经肌电图检测,以神经肌电图检查作为"金标准",将结果进行比较。结果 VPT检测与神经肌电图检测比较,VPT检测组的DPN发生率为36.00%,神经肌电图检测组为38.00%,两组比较,差异无统计学意义(P>0.05)。结论新确诊的2型糖尿病患者存在较高的DPN及糖尿病足风险,足部VPT对于新确诊的2型糖尿病患者DPN的筛查及治疗有指导作用,值得临床推广应用。Objective To explore the application effect of the vibration perception threshold （VPT） testing in screening of new-onset type 2 diabetic peripheral neuropathy（DPN）. Methods 50 newly diagnosed patients with type 2 diabetes and with- out feeling of foot numb, burning pain, stabbing pain and so on were tested by the VPT testing and the nerve electromyography re- spectively. The test results were compared with the nerve electromyography as ＂golden stangdard＂. Results The DPN incidence rate was 36.00% in the VPT group and 38.00% in the nerve electromyography group ,the difference between the two groups had no statistical significance （P〉0.05）. Conclusion The patients with newly diagnosed type 2 diabetes mellitus have the higher risk of DPN and diabetic foot. The foot VPT has the guidance function for screening and treatment of DPN in the patients with newly di- agnosed type 2 diabetes mellitus and is worthy of clinical application.

关 键 词：糖尿病 2型 并发症 肌电描记术 糖尿病神经病变 诊断 神经传导 震动感觉阈值 感觉神经传导速度 运动神经传导速度 感觉定量检测 

分 类 号：R587.2[医药卫生—内分泌]