2型糖尿病血瘀证与颈动脉内膜中层厚度相关性研究  

Correlation Studyof Blood Stasis Syndromeof Type 2 Diabetes and the IntimaMedia Thicknessof the Carotid Artery

作　　者：陈松姬[1] 陈刚[2] 林宁[3] 

机构地区：[1]福建中医药大学附属人民医院传统内科,福建福州350004 [2]福建省立医院内分泌科,福建福州350001 [3]福建省立医院超声科,福建福州350001

出　　处：《实用中医药杂志》2013年第7期515-516,共2页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:探讨2型糖尿病血瘀证与颈动脉内膜中层厚度的关系。方法:将79例分为血瘀证组与非血瘀证组,进行血瘀证症状分级量化评分并行颈动脉内膜中层厚度(IMT)检测。结果:血瘀证组49例颈动脉IMT平均为(1.173±0.250)mm,非血瘀证组30例颈动脉IMT平均为(0.930±0.167)mm,血瘀证组颈动脉IMT较非血瘀证组厚(P<0.05)。血瘀证积分与颈动脉IMT呈正相关(P<0.01),r=0.551。结论:颈动脉IMT可作为2型糖尿病中医血瘀证监测的参考指标,2型糖尿病血瘀状态可能是颈动脉IMT增厚的危险因素。Objective：The aim of this study was to explore the relationship between TCM blood stasis syndrome of type-2 diabetes mellitus and carotid intima-media thickness.Methods：According to the WHO（1999） diagnosis standard,79 type-2 diabetes mellitus patients were chosed as research objects.Then according to 2002 ＂Chinese Native Medicine New Medicine Clinical Research Guiding Principle＂ blood stasis card diagnosis standard,the patients were divided into TCM blood stasis syndrome group and non-blood stasis syndrome group.Ultrasonography of carotid intima-media thickness was performed using a high frequency linear array transducer.Results：The average carotid intima-media thickness of blood stasis syndrome group was（1.173±0.250）mm,the average carotid intima-media thickness of non-blood stasis syndrome group was（0.930±0.167）mm.The carotid intima-media thickness of blood stasis syndrome group was higher than the carotid intima-media thickness of non-blood stasis syndrome group,P＆lt;0.05.There was positive correlation between the scores of 79 type-2 diabetes mellitus and the carotid intima-media thickness,P ＆lt; 0.001,r=0.551.Conclusion：The carotid intima-media thickness may be the index to monitor TCM blood stasis card.The blood stasis of type-2 diabetes mellitus may be the risk factor of the carotid intima-media thickness increase.

关 键 词：2型糖尿病 血瘀证 颈动脉内膜中层厚度 相关性 

分 类 号：R255.487.1[医药卫生—中医内科学]